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创伤性中央脊髓综合征。

Traumatic Central Cord Syndrome.

机构信息

Department of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, NY.

Department of Neurological Surgery, Thomas Jefferson University, Philadelphia, PA.

出版信息

Clin Spine Surg. 2024 Nov 1;37(9):379-387. doi: 10.1097/BSD.0000000000001703. Epub 2024 Sep 30.

Abstract

Central cord syndrome (CCS) is the most common form of incomplete spinal cord injury, with an increasing incidence with the aging population. This is a clinical diagnosis defined by weakness greater in the upper than lower extremities and often prominent sensory complaints in the hands. CCS is typically seen in individuals with underlying cervical canal stenosis from spondylosis who experience sudden forceful movement of the neck, especially hyperextension, resulting in contusion of the spinal cord. The prognosis in CCS is relatively favorable with improvement in neurological deficits, except for fine motor control of the hands. Neuropathic pain may persist even in those with excellent motor recovery. Nonoperative management may be appropriate in selected patients, but surgery is usually necessary in those with poor neurological recovery or further deterioration. The optimal timing of surgical intervention has not been defined, but recent evidence suggests that early surgery (≤24 h) may lead to greater neurological recovery, shorter hospital stay, and fewer inpatient complications. Management in any given patient must be considered in the context of the anatomy and location of spinal cord compression, the presence of fractures or ligamentous instability, the temporal course of signs and symptoms, as well as the patient's overall health.

摘要

中央脊髓综合征(CCS)是最常见的不完全性脊髓损伤形式,随着人口老龄化,其发病率不断增加。这是一种临床诊断,其特点是上肢的无力比下肢更明显,手部常伴有明显的感觉障碍。CCS 通常发生在伴有颈椎管狭窄的颈椎病患者中,这些患者的颈部突然受到强烈的外力作用,尤其是过度伸展,导致脊髓挫伤。CCS 的预后相对较好,神经功能缺损会有所改善,但手部精细运动控制除外。即使运动功能恢复良好,神经病理性疼痛也可能持续存在。在某些患者中,非手术治疗可能是合适的,但对于神经功能恢复不良或进一步恶化的患者,通常需要手术。手术干预的最佳时机尚未确定,但最近的证据表明,早期手术(≤24 小时)可能会导致更大的神经功能恢复、更短的住院时间和更少的住院并发症。必须根据脊髓压迫的解剖结构和位置、骨折或韧带不稳定的存在、症状和体征的时间进程以及患者的整体健康状况来考虑对每位患者的治疗方案。

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