Blackstock D, Gettes M A
Can Anaesth Soc J. 1986 Jan;33(1):32-5. doi: 10.1007/BF03010905.
A study was conducted to measure the pressure in the middle ear in healthy children, following nitrous oxide anaesthesia. Premedication with chloral hydrate and scopolamine orally was similar in all patients and awake patients received thiopentone 4-5 mg X kg-1 for induction of anaesthesia. All received nitrous oxide (66 per cent) in oxygen and halothane or isoflurane as required. Exposure to nitrous oxide varied from 17-100 minutes, mean 47 minutes. All patients developed negative pressure in one or both ears in the first day following anaesthesia. This is a higher incidence than previously reported and may be explained by the inability of children to equilibrate negative middle ear pressure via the eustachian tube.
一项研究旨在测量健康儿童在氧化亚氮麻醉后中耳的压力。所有患者口服水合氯醛和东莨菪碱进行术前用药的情况相似，清醒患者接受4 - 5毫克/千克体重的硫喷妥钠用于诱导麻醉。所有人按需接受了含66%氧化亚氮的氧气以及氟烷或异氟烷。氧化亚氮暴露时间从17至100分钟不等，平均47分钟。所有患者在麻醉后的第一天一只或两只耳朵都出现了负压。这一发生率高于先前报道，可能是由于儿童无法通过咽鼓管平衡中耳负压所致。
