MMWR Morb Mortal Wkly Rep. 2024 Oct 31;73(43):978-984. doi: 10.15585/mmwr.mm7343a4.
In 2020, the World Health Assembly endorsed the Immunization Agenda 2030 (IA2030), a 10-year strategy to reduce vaccine-preventable disease (VPD)-associated morbidity and mortality. IA2030 goals include improving equitable vaccination coverage, halving the number of unimmunized (zero-dose) children, and increasing the introduction of new and underutilized vaccines. The COVID-19 pandemic disrupted health systems worldwide, hindering years of childhood vaccination achievements and putting global public health goals at risk. This report presents trends in World Health Organization (WHO) and UNICEF routine vaccination coverage estimates through 2023 across the 194 WHO member countries. During 2022-2023, global coverage with the first and third doses of diphtheria-tetanus-pertussis-containing vaccine (DTPcv) (89% and 84%, respectively) and the first dose of measles-containing vaccine (83%) stagnated and remained lower than prepandemic levels. The 31 WHO member countries with fragile, conflict-affected, and vulnerable (FCV) settings include approximately one half of the world's 14.5 million children who did not receive the first DTPcv dose. The introduction of new and underutilized vaccines, such as a second MCV dose in the African Region, has improved countries' overall protection against VPDs. Accelerating country-specific routine immunization and catch-up vaccination programs to reach unvaccinated and incompletely vaccinated children, especially those living in FCV settings, is critical to reducing morbidity and mortality associated with VPDs.
2020 年,世界卫生大会通过了《免疫议程 2030》(IA2030),这是一项为期十年的战略,旨在减少疫苗可预防疾病(VPD)相关的发病率和死亡率。IA2030 的目标包括提高公平接种覆盖率,将未接种(零剂量)儿童人数减少一半,并增加新疫苗和未充分利用疫苗的引入。COVID-19 大流行扰乱了全球卫生系统,阻碍了多年来的儿童疫苗接种成果,并使全球公共卫生目标面临风险。本报告介绍了 2023 年期间,194 个世卫组织成员国通过世卫组织和儿童基金会常规免疫覆盖估计数的趋势。在 2022-2023 年期间,白喉、破伤风、百日咳(DTPcv)疫苗第一和第三剂(分别为 89%和 84%)和麻疹疫苗第一剂(83%)的全球覆盖率停滞不前,仍低于大流行前的水平。在 31 个有脆弱、受冲突影响和易受冲击(FCV)环境的世卫组织成员国中,约有一半的世界上 1450 万未接种第一剂 DTPcv 的儿童。新疫苗和未充分利用疫苗的引入,如在非洲区域引入第二剂麻疹疫苗,提高了各国对 VPD 的总体保护水平。加快国家特定的常规免疫和补种疫苗方案,以覆盖未接种和不完全接种疫苗的儿童,特别是生活在 FCV 环境中的儿童,对于减少 VPD 相关发病率和死亡率至关重要。