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偏头痛对叙利亚社会的多方面影响:一项多中心横断面研究的启示。

The multifaceted effects of migraine on Syrian society: insights from a multicenter cross-sectional study.

机构信息

Faculty of Medicine, University of Aleppo, Aleppo, Syria.

Faculty of Medicine, Damascus University, Damascus, Syria.

出版信息

BMC Neurol. 2024 Nov 1;24(1):425. doi: 10.1186/s12883-024-03931-6.

DOI:10.1186/s12883-024-03931-6
PMID:39482573
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11529229/
Abstract

BACKGROUND

Migraine is the most common primary headache. It's alone responsible for 1.3% of disability in the world. Migraine both worsen quality of life of individuals and place a significant burden on the society. Despite this, there exists a knowledge gap regarding its repercussions on the Syrian population.

METHODS

This cross-sectional study enrolled 679 migraine-diagnosed patients from all over Syria through electronic questionnaires disseminated on official social media platforms. Depending on demographic characteristics, physical and mental debility assessed using the Chalder scale, the Migraine Specific Quality of Life Questionnaire (MSQ) and the Generalized Anxiety Disorder 2-item (GAD_2) scale.

RESULTS

Our study included 679 participants (mean age: 29.49 years; BMI: 24.55). The sample was predominantly female (74.7%) and mostly single (52%). Females reported higher fatigue (mean = 21.48) than males (mean = 19.22; p < .001). However, Males had better Migraine-Specific Quality of Life (MSQ) scores (mean = 49.90) compared to females (mean = 42.27; p < .001). Females scored higher on anxiety (GAD-2: mean = 2.99 vs. mean = 2.35; p < .001). Moreover, urban residents had higher scores on the Role Preventive (RF-P) subscale of the MSQ than rural residents (mean = 49.93 vs. mean = 44.82; p = .014). Higher fatigue and anxiety levels were associated with lower quality of life scores.

CONCLUSIONS

This study aimed to elucidate the multifaceted impact of migraines on daily life, considering diverse demographic variables to enhance diagnostic accuracy, treatment efficacy, and disease management strategies.

摘要

背景

偏头痛是最常见的原发性头痛。它独自导致了全球 1.3%的残疾。偏头痛不仅恶化了个体的生活质量,还给社会带来了巨大负担。尽管如此,对于偏头痛对叙利亚人群的影响,仍然存在知识空白。

方法

本横断面研究通过在官方社交媒体平台上发布电子问卷,从叙利亚各地招募了 679 名偏头痛确诊患者。根据人口统计学特征、使用 Chalder 量表评估的身体和精神虚弱、偏头痛特异性生活质量问卷 (MSQ) 和广泛性焦虑症 2 项 (GAD_2) 量表进行评估。

结果

我们的研究包括 679 名参与者(平均年龄:29.49 岁;BMI:24.55)。该样本主要为女性(74.7%),大多数为单身(52%)。女性报告的疲劳感(平均值=21.48)高于男性(平均值=19.22;p<.001)。然而,男性的偏头痛特异性生活质量(MSQ)评分(平均值=49.90)高于女性(平均值=42.27;p<.001)。女性的焦虑评分(GAD-2:平均值=2.99 与平均值=2.35;p<.001)较高。此外,城市居民的 MSQ 中的角色预防(RF-P)子量表评分高于农村居民(平均值=49.93 与平均值=44.82;p=.014)。较高的疲劳和焦虑水平与较低的生活质量评分相关。

结论

本研究旨在阐明偏头痛对日常生活的多方面影响,考虑到各种人口统计学变量,以提高诊断准确性、治疗效果和疾病管理策略。

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Sleep quality and mental health differences following Syria-Turkey earthquakes: A cross-sectional study.震后叙利亚与土耳其地震对睡眠质量和心理健康的影响:一项横断面研究。
Int J Soc Psychiatry. 2024 Jun;70(4):700-708. doi: 10.1177/00207640231223432. Epub 2024 Jan 26.
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Anxiety and depression and health-related quality of life among adults with migraine: a National Population-Based Study.偏头痛成年人的焦虑、抑郁与健康相关生活质量:一项全国性基于人群的研究。
Front Public Health. 2023 Oct 4;11:1241800. doi: 10.3389/fpubh.2023.1241800. eCollection 2023.
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Global, regional, and national epidemiology of migraine and tension-type headache in youths and young adults aged 15-39 years from 1990 to 2019: findings from the global burden of disease study 2019.全球、区域和国家 1990 年至 2019 年 15-39 岁青少年和青年偏头痛和紧张型头痛的流行病学:2019 年全球疾病负担研究的结果。
J Headache Pain. 2023 Sep 18;24(1):126. doi: 10.1186/s10194-023-01659-1.
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Impact of headache frequency and preventive medication failure on quality of life, functioning, and costs among individuals with migraine across several European countries: need for effective preventive treatment.在多个欧洲国家,偏头痛患者的头痛频率和预防药物失败对生活质量、功能和成本的影响:需要有效的预防治疗。
J Headache Pain. 2023 Aug 24;24(1):115. doi: 10.1186/s10194-023-01655-5.
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The demographic features of fatigue in the general population worldwide: a systematic review and meta-analysis.全球普通人群疲劳的人口统计学特征:系统评价和荟萃分析。
Front Public Health. 2023 Jul 28;11:1192121. doi: 10.3389/fpubh.2023.1192121. eCollection 2023.
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Global, regional, and national time trends in incidence for migraine, from 1990 to 2019: an age-period-cohort analysis for the GBD 2019.全球、区域和国家偏头痛发病率的时间趋势:1990 年至 2019 年的年龄-时期-队列分析:GBD 2019 研究
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