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在新冠疫情期间采用窄谱中波紫外线光疗和日光疗法治疗持久性斑疹性血管扩张症

Telangiectasia Macularis Eruptiva Perstans Treated with Narrow-Band UVB Phototherapy and Heliotherapy during the COVID-19 Pandemic.

作者信息

de Guia Christine E, Amado Alma Gay Concepcion T

机构信息

Rizal Medical Center, Pasig City, Philippines.

出版信息

Acta Med Philipp. 2023 Jul 27;57(7):64-66. doi: 10.47895/amp.v57i7.4543. eCollection 2023.

Abstract

Telangiectasia macularis eruptiva perstans (TMEP) is a rare disease, previously classified as a variant of cutaneous mastocytosis. While no gold standard of treatment exists, several treatments have been studied. We report a case of a 63-year-old woman who presented with long-standing asymptomatic telangiectatic macules beginning on the upper chest, back, and bilateral arms, with occasional pruritus and no other systemic symptoms. Skin biopsy, along with Giemsa stain, revealed findings consistent with TMEP. The patient underwent testing for serum tryptase level, which was within normal limits. The patient was started on topical steroids for two weeks and antihistamine therapy, with a noted decrease in pruritus but no change in cutaneous lesions. She was then advised to start phototherapy, and subsequently underwent a total of five sessions of narrow-band ultraviolet B phototherapy, after which she noted lightening of the lesions. Due to the COVID pandemic, the patient was shifted to heliotherapy with continued lightening of lesions after two months of thrice weekly sessions. This rare case is supportive of narrow-band ultraviolet B phototherapy and heliotherapy as promising treatment options for cases of TMEP.

摘要

持久性发疹性斑状毛细血管扩张症(TMEP)是一种罕见疾病,以前被归类为皮肤肥大细胞增多症的一种变体。虽然不存在治疗的金标准,但已经对几种治疗方法进行了研究。我们报告了一例63岁女性病例,该患者自上胸部、背部和双侧手臂开始出现长期无症状的毛细血管扩张性斑疹,伴有偶尔瘙痒,无其他全身症状。皮肤活检及吉姆萨染色显示结果与TMEP一致。患者接受了血清类胰蛋白酶水平检测,结果在正常范围内。患者开始使用外用类固醇治疗两周并进行抗组胺治疗,瘙痒明显减轻,但皮肤病变无变化。随后建议她开始光疗,随后总共接受了5次窄谱中波紫外线光疗,之后她注意到病变变浅。由于新冠疫情,患者转而接受日光疗法,每周三次,两个月后病变持续变浅。这个罕见病例支持窄谱中波紫外线光疗和日光疗法作为TMEP病例有前景的治疗选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e2d/11522599/210b6b74269d/AMP-57-7-4543-g001.jpg

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