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具核梭杆菌心内膜炎合并颅内脓肿:一例报告并文献复习

Fusobacterium necrophorum endocarditis with intracranial abscesses: A case report and review of the literature.

作者信息

Wong Emily, Robinson Clark, Upadhyaya Parth, Chandra Alvin, Prokesch Bonnie C, Kang Minji

机构信息

Division of Infectious Disease, Department of Internal Medicine, UT Southwestern Medical Center, Dallas, TX, USA.

Division of Hematology and Oncology, Department of Internal Medicine, UT Southwestern Medical Center, Dallas, TX, USA.

出版信息

J Cardiol Cases. 2024 May 31;30(3):75-78. doi: 10.1016/j.jccase.2024.05.005. eCollection 2024 Sep.

DOI:10.1016/j.jccase.2024.05.005
PMID:39483409
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11523196/
Abstract

UNLABELLED

species are obligate anaerobic Gram-negative bacilli that are non-spore forming. The two most common species tied to human disease are and They are commensal organisms in the oropharynx, gastrointestinal tract, and genital tract of humans, but can cause invasive infections especially in the head and neck such as periodontal disease and Lemierre's syndrome. is an uncommon cause of infective endocarditis. We present a case of a previously healthy male who developed endocarditis with multiple sites of pyogenic abscess formation.

LEARNING OBJECTIVE

Even among anaerobes, which account for less than 1 % of infective endocarditis (IE) cases, is rare. Specific laboratory conditions are necessary for growth, leading to delays in diagnosis. Severe disease is common given its virulence and predisposition for thrombophlebitis. While uncommon, it is crucial to maintain a degree of suspicion for IE especially in individuals without prior cardiac disease whose infections were preceded by potential head and neck source.

摘要

未标注

该菌种为专性厌氧革兰氏阴性杆菌,不形成芽孢。与人类疾病相关的两种最常见菌种是[具体菌种1]和[具体菌种2]。它们是人类口咽、胃肠道和生殖道中的共生生物,但可引起侵袭性感染,尤其是在头颈部,如牙周病和勒米尔综合征。[具体菌种1]是感染性心内膜炎的罕见病因。我们报告一例既往健康男性发生[具体菌种1]心内膜炎并伴有多处化脓性脓肿形成的病例。

学习目标

即使在占感染性心内膜炎(IE)病例不到1%的厌氧菌中,[具体菌种1]也很罕见。其生长需要特定的实验室条件,导致诊断延迟。鉴于其毒力和血栓性静脉炎倾向,严重疾病很常见。虽然不常见,但对于[具体菌种1]性心内膜炎保持一定程度的怀疑至关重要,尤其是在没有心脏病史且感染之前有潜在头颈部感染源的个体中。

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本文引用的文献

1
Fusobacterium necrophorum Endocarditis with Liver Abscesses: A Case Report and Review of the Literature.坏死梭杆菌心内膜炎合并肝脓肿:病例报告及文献复习。
Intern Med. 2021 Aug 1;60(15):2445-2449. doi: 10.2169/internalmedicine.6348-20. Epub 2021 Mar 1.
2
A Curious Case of Endocarditis and Liver Abscess in a Previously Healthy Man.一名既往健康男性的罕见心内膜炎和肝脓肿病例
Am J Med. 2020 Feb;133(2):186-190. doi: 10.1016/j.amjmed.2019.07.023. Epub 2019 Aug 14.
3
First case of Fusobacterium necrophorum endocarditis to have presented after the 2nd decade of life.坏死梭杆菌性心内膜炎首例发病于生命的第二个十年之后。
Tex Heart Inst J. 2013;40(4):449-52.
4
Fusobacterium necrophorum causing infective endocarditis and liver and splenic abscesses.坏死梭杆菌引起感染性心内膜炎及肝脾脓肿。
Rev Inst Med Trop Sao Paulo. 2011 May-Jun;53(3):169-72. doi: 10.1590/s0036-46652011000300009.
5
Fusobacterium necrophorum endocarditis Case report and review of the literature.坏死梭杆菌心内膜炎病例报告及文献复习。
Diagn Microbiol Infect Dis. 2011 Feb;69(2):192-5. doi: 10.1016/j.diagmicrobio.2010.09.014.
6
Fatal case of Fusobacterium necrophorum mitral endocarditis.坏死梭杆菌性二尖瓣心内膜炎致死病例。
J Infect. 2010 Jul;61(1):94-5. doi: 10.1016/j.jinf.2010.03.031. Epub 2010 Apr 8.
7
Human infection with Fusobacterium necrophorum (Necrobacillosis), with a focus on Lemierre's syndrome.人类感染坏死梭杆菌(坏死杆菌病),重点关注勒米尔综合征。
Clin Microbiol Rev. 2007 Oct;20(4):622-59. doi: 10.1128/CMR.00011-07.
8
Fusobacterium necrophorum endocarditis in a previously healthy young adult.一名既往健康的年轻成年人患坏死梭杆菌性心内膜炎。
Am J Med Sci. 2007 Aug;334(2):125-7. doi: 10.1097/MAJ.0b013e31812f5ad1.
9
Fusobacterium necrophorum septicemia.坏死梭杆菌败血症
JAMA. 1983 Jul 1;250(1):35.
10
Anaerobic bacterial endocarditis.厌氧性细菌性心内膜炎
N Engl J Med. 1970 Nov 26;283(22):1188-92. doi: 10.1056/NEJM197011262832203.