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因接触金属烟雾和硝酸导致的职业性弥漫性肺泡出血:一例报告

Occupational Diffuse Alveolar Hemorrhage Due to Metal Fume and Nitric Acid Exposure: A Case Report.

作者信息

Hattori Mototaka, Nagashima Akimichi, Abe Keiko, Kasai Shogo, Okochi Yasumi

机构信息

Department of Respiratory Medicine, Japan Community Healthcare Organization Tokyo Yamate Medical Center, Tokyo, JPN.

Department of Pathology, Japan Community Healthcare Organization Tokyo Yamate Medical Center, Tokyo, JPN.

出版信息

Cureus. 2024 Oct 1;16(10):e70618. doi: 10.7759/cureus.70618. eCollection 2024 Oct.

DOI:10.7759/cureus.70618
PMID:39483597
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11526617/
Abstract

A 52-year-old male welder, who had been exposed to metal fumes and nitric acid without adequate protective measures, presented with symptoms of cough, dyspnea, and fever. He was admitted to our hospital, where bronchoscopy revealed hemorrhagic bronchoalveolar lavage fluid. He was diagnosed with diffuse alveolar hemorrhage (DAH) due to occupational inhalation of metal fumes and nitric acid. Treatment with corticosteroids led to a rapid recovery without pulmonary sequelae. The case highlights the potential for metal fumes and/or nitric acid to induce DAH, the effectiveness of corticosteroids in treating the condition, and the critical importance of occupational protective measures.

摘要

一名52岁的男性焊工,在没有采取足够防护措施的情况下接触了金属烟雾和硝酸,出现咳嗽、呼吸困难和发热症状。他被收治入我院,支气管镜检查显示支气管肺泡灌洗液呈血性。他被诊断为因职业性吸入金属烟雾和硝酸导致的弥漫性肺泡出血(DAH)。使用皮质类固醇治疗后迅速康复,未留下肺部后遗症。该病例凸显了金属烟雾和/或硝酸诱发DAH的可能性、皮质类固醇治疗该病的有效性以及职业防护措施的至关重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c430/11526617/f5a79debcd78/cureus-0016-00000070618-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c430/11526617/a839a6f0032d/cureus-0016-00000070618-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c430/11526617/54baaa510dc0/cureus-0016-00000070618-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c430/11526617/f5a79debcd78/cureus-0016-00000070618-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c430/11526617/a839a6f0032d/cureus-0016-00000070618-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c430/11526617/54baaa510dc0/cureus-0016-00000070618-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c430/11526617/f5a79debcd78/cureus-0016-00000070618-i03.jpg

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Int J Mol Sci. 2021 Jan 14;22(2):793. doi: 10.3390/ijms22020793.
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Diffuse alveolar hemorrhage: how relevant is etiology?弥漫性肺泡出血:病因的相关性如何?
Sarcoidosis Vasc Diffuse Lung Dis. 2019;36(1):47-52. doi: 10.36141/svdld.v36i1.7160. Epub 2019 May 1.
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