Zhao Zhenqing, Jin Yinbing, Ma Huaibao, Lu Mingfeng
Department of Emergency Department, Northern Jiangsu People's Hospital Affiliated to Yangzhou University, Yangzhou, 225001, China.
Xuzhou Medical University, Xuzhou, 221000, China.
BMC Pulm Med. 2025 Jul 2;25(1):298. doi: 10.1186/s12890-025-03758-y.
Concentrated nitric acid can form nitrogen oxides through a spontaneous redox reaction. After inhalation, it has a stimulating effect on the respiratory tract and can cause inhalation lung injury. This lung injury is mainly manifested as non-cardiogenic pulmonary edema in imaging, and pulmonary ultrasound can dynamically monitor the severity of pulmonary edema at the patient's bedside.
This article describes a 52-year-old female case who experienced chest tightness and dyspnea 8 h after inhaling nitric acid fumes and was sent to the emergency room. Chest CT suggested diffuse exudation in both lungs, and dynamic B-lines could be seen by bedside pulmonary ultrasound. During the treatment of this patient, we adjusted the dosage of hormones and the oxygen therapy plan in a timely manner according to the evolution of B-lines under ultrasound. After treatment, her clinical symptoms gradually improved, and the re-examination of chest CT showed that the exudation in both lungs was gradually absorbed.
This case reminds clinicians to be alert to the occurrence of delayed pulmonary edema when treating patients who inhale nitric acid fumes. At the same time, dynamic examination of bedside pulmonary ultrasound is of great value in the treatment of such patients.
浓硝酸可通过自发的氧化还原反应生成氮氧化物。吸入后,它对呼吸道有刺激作用,可导致吸入性肺损伤。这种肺损伤在影像学上主要表现为非心源性肺水肿,而肺部超声可在患者床边动态监测肺水肿的严重程度。
本文描述了一名52岁女性病例,该患者吸入硝酸烟雾8小时后出现胸闷、呼吸困难,被送往急诊室。胸部CT提示双肺弥漫性渗出,床边肺部超声可见动态B线。在该患者的治疗过程中,我们根据超声下B线的演变及时调整了激素剂量和氧疗方案。治疗后,她的临床症状逐渐改善,胸部CT复查显示双肺渗出逐渐吸收。
该病例提醒临床医生在治疗吸入硝酸烟雾的患者时要警惕迟发性肺水肿的发生。同时,床边肺部超声动态检查对这类患者的治疗具有重要价值。