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毛里求斯阻塞性睡眠呼吸暂停患者的人体测量指标

Anthropometric Indices of Obstructive Sleep Apnea Patients in Mauritius.

作者信息

Sant Bakshsingh Vibhootee, Manraj Meera, Pillai Devaraj Keser-I-Hind, Suhootoorah Fateemah, Boodhun Abdool Arbaaz, Soreefan Sidrah Bibi

机构信息

Faculty of Medicine, University of Mauritius, Reduit, MUS.

出版信息

Cureus. 2024 Oct 30;16(10):e72708. doi: 10.7759/cureus.72708. eCollection 2024 Oct.

Abstract

Background Obstructive sleep apnea (OSA) is the most prevalent sleep-related breathing disorder, affecting a significant number of individuals globally. It is associated with poor quality of life and an increased risk of all-cause mortality. It is estimated that most of the patients suffering from OSA are obese. Anthropometric indices can help guide doctors toward the diagnosis. Objectives This study aimed to establish specific anthropometric thresholds associated with OSA risk, allowing clinicians to identify individuals more likely to have OSA and who may need further evaluation, such as polysomnography. This targeted screening approach would enable better resource allocation to those at higher risk, potentially enhancing the efficiency of OSA diagnosis and management. Methods We conducted a descriptive study using data from the sole private sleep clinic in Mauritius. We analyzed case files of consecutive patients diagnosed with OSA over a 3.5-year period from January 2015 to June 2018. Results The study population comprised 170 patients (79.4% males) diagnosed with OSA by a polygraphy test. The mean age of OSA diagnosis in men and women was 51.7 ± 14.0 years and 53.8 ± 12.5 years, respectively. The mean neck circumference (NC) for males and females was 41.9 ± 3.9 cm and 38.2 ± 3.9 cm, while the mean waist circumference (WC) was 105.6 ± 12.2 cm for men and 103.4 ± 14.5 cm for women. The body mass index (BMI) was 29.1 ± 5.0 kg/m and 31.4 ± 6.8 kg/m for males and females, respectively. The apnea-hypopnea index (AHI) averaged to 42.1 ± 19.7 events/hour for men and 33.3 ± 16.4 events/hour for women. In male patients, we found a positive significant correlation (p<0.001) between AHI and the following parameters: BMI (r=0.443), WC (r=0.337), WC-to-height ratio (WHr) (r=0.378), NC (r =0.274), and neck-to-height ratio (NHr) (r =0.321). In women, we observed a positive significant correlation between apnea severity and the following: BMI (r=0.396, p=0.029), WC (r=0.462, p=0.005), and WHr (r=0.494, p=0.003). No significant relationships were observed between AHI and the following parameters in women: NC (r=0.317, p=0.064) and NHr (r=0.311, p=0.069). A total of 83.5% of patients had a Mallampati score of 3-4. Conclusion This study represents a pioneering effort on the island. While further research is necessary to establish exact anthropometric cutoff values, the findings offer crucial insights for physicians to identify high-risk individuals. With just a scale, measuring tape, and calculator, healthcare professionals can detect important health markers that extend beyond diagnosing OSA. These simple measurements not only help in predicting OSA but also provide a broader view of an individual's overall health, identifying risks that go beyond sleep issues. This research sets an important foundation for future OSA studies within the Mauritian population.

摘要

背景 阻塞性睡眠呼吸暂停(OSA)是最常见的与睡眠相关的呼吸障碍,全球有大量人群受其影响。它与生活质量差和全因死亡率增加有关。据估计,大多数患有OSA的患者都肥胖。人体测量指标有助于指导医生进行诊断。目的 本研究旨在确定与OSA风险相关的特定人体测量阈值,使临床医生能够识别更有可能患有OSA且可能需要进一步评估(如多导睡眠图)的个体。这种有针对性的筛查方法将使能更好地为高风险人群分配资源,有可能提高OSA诊断和管理的效率。方法 我们使用毛里求斯唯一一家私立睡眠诊所的数据进行了一项描述性研究。我们分析了2015年1月至2018年6月这3.5年期间连续诊断为OSA的患者的病历。结果 研究人群包括170例经多导睡眠图测试诊断为OSA的患者(79.4%为男性)。男性和女性OSA诊断的平均年龄分别为51.7±14.0岁和53.8±12.5岁。男性和女性的平均颈围(NC)分别为41.9±3.9厘米和38.2±3.9厘米,而男性和女性的平均腰围(WC)分别为105.6±12.2厘米和103.4±14.5厘米。男性和女性的体重指数(BMI)分别为29.1±5.0千克/米²和31.4±6.8千克/米²。男性的呼吸暂停低通气指数(AHI)平均为42.1±19.7次/小时,女性为33.3±16.4次/小时。在男性患者中,我们发现AHI与以下参数之间存在显著正相关(p<0.001):BMI(r=0.443)、WC(r=0.337)、腰围身高比(WHr)(r=0.378)、NC(r =0.274)和颈高比(NHr)(r =0.321)。在女性中,我们观察到呼吸暂停严重程度与以下参数之间存在显著正相关:BMI(r=0.396,p=0.029)、WC(r=0.462,p=0.005)和WHr(r=0.494,p=0.003)。在女性中,未观察到AHI与以下参数之间有显著关系:NC(r=0.317,p=0.064)和NHr(r=0.311,p=0.069)。共有83.5%的患者Mallampati评分为3 - 4分。结论 本研究是该岛的一项开创性工作。虽然需要进一步研究来确定确切的人体测量临界值,但研究结果为医生识别高危个体提供了重要见解。仅用一把秤、卷尺和计算器,医疗保健专业人员就能检测出超出OSA诊断范围的重要健康指标。这些简单的测量不仅有助于预测OSA,还能更全面地了解个体的整体健康状况,识别出超出睡眠问题的风险。这项研究为未来在毛里求斯人群中开展OSA研究奠定了重要基础。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a4c9/11527503/7446c12f3508/cureus-0016-00000072708-i01.jpg

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