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伴有C2转移累及的患者中齿状突重塑与枕髁稳定术

Odontoid remodeling with occipital condyle stabilization in patients with metastatic C2 involvement.

作者信息

Akgun Mehmet Yigit, Durmus Nazenin, Gunerbuyuk Caner, Gunara Sezer Onur, Oktenoglu Tunc, Sasani Mehdi, Ates Ozkan, Ozer Ali Fahir

机构信息

Spine Center, Koc University Hospital, Istanbul, Turkey.

Department of Neurosurgery, Koc University Hospital, Istanbul, Turkey.

出版信息

J Craniovertebr Junction Spine. 2024 Jul-Sep;15(3):367-370. doi: 10.4103/jcvjs.jcvjs_83_24. Epub 2024 Sep 12.

Abstract

The occipitocervical junction (OCJ) is a complex anatomical region crucial for protecting the lower brain stem, upper spinal cord, and lower cranial nerves. Instability in this area can lead to severe outcomes such as chronic pain, neurological deficits, or death. Various surgical techniques have been developed for OCJ stabilization, particularly using occipital condyle screws, which have shown promise in providing stability and preserving neck rotation. This article presents two cases of OCJ instability caused by metastatic involvement of the C2 vertebra, managed successfully with occipital condyle screw fixation. The first case involved a 22-year-old female with Ewing sarcoma metastasis, and the second case involved a 62-year-old male with multiple myeloma. Both patients exhibited significant improvements in neurological function and cervical stability postoperatively, with observable den remodeling. Our findings suggest that occipital condyle screw fixation is not only feasible but also effective in managing OCJ instability due to metastatic disease. Detailed preoperative evaluation and the use of advanced intraoperative imaging technologies, such as the O-arm and neuronavigation, are essential for maximizing safety and ensuring optimal outcomes. This study underscores the potential of occipital condyle screw fixation as a primary surgical method for stabilizing the OCJ in appropriate cases.

摘要

枕颈交界区(OCJ)是一个复杂的解剖区域,对于保护脑干下部、脊髓上部和颅神经下部至关重要。该区域的不稳定可导致严重后果,如慢性疼痛、神经功能缺损或死亡。已经开发了各种手术技术用于枕颈交界区稳定,特别是使用枕髁螺钉,其在提供稳定性和保留颈部旋转方面显示出前景。本文介绍了两例由C2椎体转移累及导致的枕颈交界区不稳定病例,通过枕髁螺钉固定成功治疗。第一例涉及一名22岁患有尤因肉瘤转移的女性,第二例涉及一名62岁患有多发性骨髓瘤的男性。两名患者术后神经功能和颈椎稳定性均有显著改善,可见齿状突重塑。我们的研究结果表明,枕髁螺钉固定不仅可行,而且在治疗转移性疾病导致的枕颈交界区不稳定方面有效。详细的术前评估以及使用先进的术中成像技术,如O型臂和神经导航,对于最大限度地提高安全性和确保最佳结果至关重要。本研究强调了枕髁螺钉固定作为在适当病例中稳定枕颈交界区的主要手术方法的潜力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1226/11524555/271cda76b8f2/JCVJS-15-367-g001.jpg

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