肉芽肿性多血管炎导致严重主动脉瓣反流。
Granulomatosis With Polyangiitis Causing Severe Aortic Regurgitation.
作者信息
Fabre Katarina L, Ellis Megan, Schmitz Katlin T, Daly Richard C, Layman Andrew, Maleszewski Joseph J, Julakanti Raghav, Bird Jared G
机构信息
Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA.
Department of Cardiovascular Surgery, Mayo Clinic, Rochester, Minnesota, USA.
出版信息
JACC Case Rep. 2024 Oct 2;29(19):102579. doi: 10.1016/j.jaccas.2024.102579.
Cardiac granulomatosis with polyangiitis is a rare necrotizing vasculitis impacting small to medium vessels. We present a case of granulomatosis with polyangiitis causing acute aortic valve regurgitation. Imaging reveals valve thickening, inflammation without destruction. Treatment involves glucocorticoids and rituximab for remission, with consideration of surgery for severe valve disease.
伴有多血管炎的心脏肉芽肿病是一种罕见的坏死性血管炎，累及中小血管。我们报告一例伴有多血管炎的肉芽肿病导致急性主动脉瓣反流的病例。影像学检查显示瓣膜增厚、炎症但无破坏。治疗包括使用糖皮质激素和利妥昔单抗诱导缓解，对于严重瓣膜疾病考虑手术治疗。
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