Epiconcept, Paris, France.
These authors contributed equally to this work and share first authorship. The other co-authors are listed in the alphabetical order of their countries.
Euro Surveill. 2024 Oct;29(44). doi: 10.2807/1560-7917.ES.2024.29.44.2400680.
COVID-19 vaccination recommendations include healthcare workers (HCWs). We measured COVID-19 vaccine effectiveness (CVE) of the autumn 2023 dose against laboratory-confirmed SARS-CoV-2 infection in a prospective cohort study of 1,305 HCWs from 13 European hospitals. Overall CVE was 22% (95% CI: -17 to 48), 49% (95% CI: -8 to 76) before and -11% (95% CI: -84 to 34) after the start of BA.2.86/JN.1 predominant circulation. Autumn 2023 COVID-19 vaccination led to a moderate-to-low reduction in SARS-CoV-2 infection incidence in HCWs. Monitoring of CVE is crucial for COVID-19 prevention.
COVID-19 疫苗接种建议包括医护人员（HCWs）。我们在一项针对来自欧洲 13 家医院的 1305 名 HCWs 的前瞻性队列研究中，测量了 2023 年秋季剂量对实验室确诊的 SARS-CoV-2 感染的 COVID-19 疫苗有效性（CVE）。总体 CVE 为 22%（95%CI：-17%至 48%），在 BA.2.86/JN.1 占主导地位之前为 49%（95%CI：-8%至 76%），之后为-11%（95%CI：-84%至 34%）循环。2023 年秋季 COVID-19 疫苗接种导致 HCWs 中 SARS-CoV-2 感染发病率的中等到低降低。对 CVE 的监测对于 COVID-19 的预防至关重要。
