Xhaferi Anisa, Bino Silvia, Daja Rovena, Vasili Adela, Sulo Jonilda, Mebonia Nana, Ndreu Earta, Nika Miljana, Jani Nadire, Dabaj Ermiona, Sustarova Nensi, Moçi Anila, Toçi Dorina, Fico Albana, Tomini Eugena, Robinson Sara, Jorgensen Pernille, Katz Mark A
Institute of Public Health, Tirana, Albania.
Mediterranean and Black Sea Programme in Intervention Epidemiology Training (MediPIET), European Centre for Disease Prevention and Control (ECDC) fellow, Stockholm, Sweden.
Clin Infect Dis. 2025 Aug 1;81(1):30-40. doi: 10.1093/cid/ciaf202.
Healthcare workers (HCWs) are a priority group for coronavirus disease 2019 (COVID-19) and influenza vaccination. We evaluated sociodemographic and occupational factors, attitudes, and knowledge associated with the uptake of primary and booster doses of COVID-19 and seasonal influenza vaccines among HCWs.
Between February 2022 and February 2023, we administered a structured questionnaire to HCWs in 3 Albanian hospitals who were enrolled in a multiyear cohort study. The questionnaire assessed participants' knowledge, confidence, and attitudes toward COVID-19 and seasonal influenza vaccines, and included questions on COVID-19 and influenza vaccination history, perceptions of vaccine safety and effectiveness, and factors influencing vaccine decision-making.
We included 1456 HCWs. Their median age was 44 (interquartile range: 33-53) and 77.3% were female. Overall, 20.7% were physicians, 47.0% nurses or midwives, and 21.5% support staff. In all, 93.6% received a COVID-19 primary vaccine series, 20% a COVID-19 booster, and 23.7% received an influenza vaccine in the 2022-2023 season. In the multivariable analysis, male HCWs were more likely to receive COVID-19 boosters (adjusted odds ratio [aOR] 2.08; 95% confidence interval [CI]: 1.55-2.80). However, they were less likely to receive influenza vaccines (aOR 0.69; 95% CI: .51-.95). Medical doctors were more likely to receive COVID-19 vaccine doses, while nurses had higher uptake of the influenza vaccine (aOR 1.87; 95% CI: 1.30-2.68). Confidence in the safety and effectivity of both vaccines was positively associated with vaccine uptake.
Among HCWs, primary series COVID-19 vaccine coverage was high, but COVID-19 booster doses and seasonal influenza vaccines were low. Findings related to age and sex differences among HCW groups with low vaccine uptake, as well as their knowledge and attitudes toward vaccines, should inform targeted strategies to improve COVID-19 and influenza vaccine uptake, particularly among younger HCWs, female HCWs, and nonphysicians.
医护人员是2019冠状病毒病(COVID-19)和流感疫苗接种的优先群体。我们评估了与医护人员接种COVID-19和季节性流感疫苗的首剂和加强剂相关的社会人口学和职业因素、态度及知识。
在2022年2月至2023年2月期间,我们向参与一项多年队列研究的3家阿尔巴尼亚医院的医护人员发放了一份结构化问卷。该问卷评估了参与者对COVID-19和季节性流感疫苗的知识、信心及态度,包括关于COVID-19和流感疫苗接种史、对疫苗安全性和有效性的认知以及影响疫苗决策的因素等问题。
我们纳入了1456名医护人员。他们的年龄中位数为44岁(四分位间距:33 - 53岁),77.3%为女性。总体而言,20.7%是医生,47.0%是护士或助产士,21.5%是辅助人员。在2022 - 2023季节,93.6%的人接种了COVID-19首剂疫苗系列,20%接种了COVID-19加强剂,23.7%接种了流感疫苗。在多变量分析中,男性医护人员更有可能接种COVID-19加强剂(调整后的优势比[aOR]为2.08;95%置信区间[CI]:1.55 - 2.80)。然而,他们接种流感疫苗的可能性较小(aOR为0.69;95% CI:0.51 - 0.95)。医生更有可能接种COVID-19疫苗剂次,而护士接种流感疫苗的比例更高(aOR为1.87;95% CI:1.30 - 2.68)。对两种疫苗安全性和有效性的信心与疫苗接种呈正相关。
在医护人员中,COVID-19首剂疫苗接种覆盖率较高,但COVID-19加强剂和季节性流感疫苗接种率较低。与疫苗接种率低的医护人员群体中的年龄和性别差异以及他们对疫苗的知识和态度相关的研究结果,应为改善COVID-19和流感疫苗接种情况的针对性策略提供参考,特别是在年轻医护人员、女性医护人员和非医生群体中。