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Datopotamab Deruxtecan in Advanced or Metastatic HR+/HER2- and Triple-Negative Breast Cancer: Results From the Phase I TROPION-PanTumor01 Study.在晚期或转移性 HR+/HER2-和三阴性乳腺癌中应用德曲妥珠单抗偶联物:TROPION-PanTumor01 研究的 I 期结果。
J Clin Oncol. 2024 Jul 1;42(19):2281-2294. doi: 10.1200/JCO.23.01909. Epub 2024 Apr 23.
2
Comprehensive Inherited Risk Estimation for Risk-Based Breast Cancer Screening in Women.基于风险的女性乳腺癌筛查综合遗传风险评估。
J Clin Oncol. 2024 May 1;42(13):1477-1487. doi: 10.1200/JCO.23.00295. Epub 2024 Feb 29.
3
Trastuzumab deruxtecan versus treatment of physician's choice in patients with HER2-positive metastatic breast cancer (DESTINY-Breast02): a randomised, open-label, multicentre, phase 3 trial.曲妥珠单抗-德鲁替康与医生选择的治疗方案用于治疗人表皮生长因子受体 2(HER2)阳性转移性乳腺癌患者(DESTINY-Breast02):一项随机、开放标签、多中心、III 期临床试验。
Lancet. 2023 May 27;401(10390):1773-1785. doi: 10.1016/S0140-6736(23)00725-0. Epub 2023 Apr 20.
4
Polygenic risk scores and breast cancer risk prediction.多基因风险评分与乳腺癌风险预测。
Breast. 2023 Feb;67:71-77. doi: 10.1016/j.breast.2023.01.003. Epub 2023 Jan 10.
5
Overview of the 2022 WHO Classification of Neuroendocrine Neoplasms.《2022 年世卫组织神经内分泌肿瘤分类概述》。
Endocr Pathol. 2022 Mar;33(1):115-154. doi: 10.1007/s12022-022-09708-2. Epub 2022 Mar 16.
6
Event-free Survival with Pembrolizumab in Early Triple-Negative Breast Cancer.帕博利珠单抗治疗早期三阴性乳腺癌无事件生存。
N Engl J Med. 2022 Feb 10;386(6):556-567. doi: 10.1056/NEJMoa2112651.
7
Multi-omic machine learning predictor of breast cancer therapy response.乳腺癌治疗反应的多组学机器学习预测器。
Nature. 2022 Jan;601(7894):623-629. doi: 10.1038/s41586-021-04278-5. Epub 2021 Dec 7.
8
Whole-genome analysis of Nigerian patients with breast cancer reveals ethnic-driven somatic evolution and distinct genomic subtypes.对尼日利亚乳腺癌患者的全基因组分析揭示了种族驱动的体细胞进化和不同的基因组亚型。
Nat Commun. 2021 Nov 26;12(1):6946. doi: 10.1038/s41467-021-27079-w.
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The impact of site-specific digital histology signatures on deep learning model accuracy and bias.基于组织特异性数字组织学特征对深度学习模型准确性和偏差的影响。
Nat Commun. 2021 Jul 20;12(1):4423. doi: 10.1038/s41467-021-24698-1.
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Adjuvant Olaparib for Patients with - or -Mutated Breast Cancer.奥拉帕利辅助治疗 - 或 - 突变型乳腺癌患者。
N Engl J Med. 2021 Jun 24;384(25):2394-2405. doi: 10.1056/NEJMoa2105215. Epub 2021 Jun 3.

The convergence of genomic medicine and translational omics in transforming breast cancer patient care.

作者信息

Wu Sulin, Zheng Yonglan, Olopade Olufunmilayo I

机构信息

Section of Hematology and Oncology, Department of Medicine and.

Center for Clinical Cancer Genetics & Global Health, Department of Medicine, The University of Chicago, Chicago, Illinois, USA.

出版信息

J Clin Invest. 2024 Nov 1;134(21):e187520. doi: 10.1172/JCI187520.

DOI:10.1172/JCI187520
PMID:39484719
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11527438/
Abstract
摘要