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Cancer complexity: why we need a novel cancer research strategy.

作者信息

Bredberg Anders

机构信息

Department of Laboratory Medicine, Lund University, Lund, Sweden.

Department of Medical Microbiology, Innlandet Hospital Trust, Lillehammer, Norway.

出版信息

Front Oncol. 2025 Aug 1;15:1624467. doi: 10.3389/fonc.2025.1624467. eCollection 2025.

DOI:10.3389/fonc.2025.1624467
PMID:40823070
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12353748/
Abstract
摘要

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Complexity myths and the misappropriation of evolutionary theory.复杂性神话与进化理论的滥用
Proc Natl Acad Sci U S A. 2025 Jun 10;122(23):e2425772122. doi: 10.1073/pnas.2425772122. Epub 2025 May 23.
3
Advancing Cancer Treatment: A Review of Immune Checkpoint Inhibitors and Combination Strategies.推进癌症治疗:免疫检查点抑制剂及联合策略综述
Cancers (Basel). 2025 Apr 23;17(9):1408. doi: 10.3390/cancers17091408.
4
Clinical translation of microbiome research.微生物组研究的临床转化
Nat Med. 2025 Apr;31(4):1099-1113. doi: 10.1038/s41591-025-03615-9. Epub 2025 Apr 11.
5
Impact of the ONCOBIOME network in cancer microbiome research.ONCOBIOME网络在癌症微生物组研究中的影响。
Nat Med. 2025 Apr;31(4):1085-1098. doi: 10.1038/s41591-025-03608-8. Epub 2025 Apr 11.
6
The future of cancer research: invest now.癌症研究的未来:现在就投资。
Trends Cancer. 2025 Apr;11(4):259-260. doi: 10.1016/j.trecan.2025.03.007. Epub 2025 Mar 24.
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No evidence for Peto's paradox in terrestrial vertebrates.陆地脊椎动物中不存在佩托悖论的证据。
Proc Natl Acad Sci U S A. 2025 Mar 4;122(9):e2422861122. doi: 10.1073/pnas.2422861122. Epub 2025 Feb 24.
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Checkpoint Immunotherapy for Melanoma - Offering Hope for Cure.黑色素瘤的免疫检查点疗法——带来治愈希望
N Engl J Med. 2025 Jan 2;392(1):81-82. doi: 10.1056/NEJMe2412226.
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Pan-cancer and multiomics: advanced strategies for diagnosis, prognosis, and therapy in the complex genetic and molecular universe of cancer.泛癌与多组学:癌症复杂遗传和分子领域中的诊断、预后及治疗的先进策略
Clin Transl Oncol. 2024 Dec 26. doi: 10.1007/s12094-024-03819-4.
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Conventional chemotherapy: millions of cures, unresolved therapeutic index.传统化疗:数百万次治愈,未解决的治疗指数。
Nat Rev Cancer. 2025 Mar;25(3):209-218. doi: 10.1038/s41568-024-00778-4. Epub 2024 Dec 16.