Koppert H C, Hellemans A C
Doc Ophthalmol. 1986 Jan 15;61(3-4):211-7. doi: 10.1007/BF00142344.
The results of surveys among 188 primary school children in two hyperendemic rain-forest villages in South-West Cameroon are reported. The children were examined for their nutritional state and for lesions due to onchocerciasis, with emphasis on eye pathology. Clinical manifestations in the two villages hyperendemic for onchocerciasis were compared with those found in a hypo-endemic coastal village. The primary school age appeared to be the period with the highest increase in ocular, notably corneal, involvement in onchocerciasis. The prevalence of ocular involvement showed an increase from 42.8% in the 6-year age group to 100% in the 12-year age group. 17.5% of the children were considered to be at risk of developing serious ocular onchocerciasis. Significant correlation between nutritional state and severity of infection could not be demonstrated. Sex differences in onchocercal symptomatology appeared not to be significant. The importance of microfilarial concentration in the skin snip near the eye is stressed as a simple but important indicator of danger to the eye. Prognosis and therapy are discussed.
报告了对喀麦隆西南部两个盘尾丝虫病高度流行雨林村庄的188名小学生进行调查的结果。对这些儿童进行了营养状况检查以及盘尾丝虫病所致病变检查，重点是眼部病理学检查。将盘尾丝虫病高度流行的两个村庄的临床表现与一个低度流行的沿海村庄的临床表现进行了比较。小学年龄似乎是盘尾丝虫病眼部尤其是角膜受累增加最多的时期。眼部受累患病率从6岁年龄组的42.8%增至12岁年龄组的100%。17.5%的儿童被认为有发生严重眼部盘尾丝虫病的风险。未证实营养状况与感染严重程度之间存在显著相关性。盘尾丝虫病症状学的性别差异似乎不显著。强调了眼部附近皮肤切片中微丝蚴浓度作为眼部危险的一个简单但重要指标的重要性。对预后和治疗进行了讨论。
