Taylor H R
Bull World Health Organ. 1984;62(4):509-15.
The treatment of onchocerciasis using diethylcarbamazine and suramin sodium, which can kill different stages of the parasite, Onchocerca volvulus, remains unsatisfactory. Recent studies have more clearly defined the serious limitations of the existing forms of treatment. However, two new classes of compounds, the benzimidazoles and avermectins, offer exciting new leads in the search for a safe and effective treatment that could be used on a large scale.
使用能杀死寄生虫旋盘尾丝虫不同阶段的乙胺嗪和苏拉明钠治疗盘尾丝虫病,效果仍不尽人意。近期研究更清晰地界定了现有治疗形式的严重局限性。然而,两类新型化合物——苯并咪唑类和阿维菌素类,为寻找可大规模使用的安全有效治疗方法提供了令人振奋的新线索。