Pouchin Pauline, Michaël Genin, Simona Bara, Nicolas Vigneron, Launoy Guy, Bryère Joséphine
Anticipe Unit, Caen, France
CHU Lille, ULR 2694 - METRICS : Évaluation des technologies de santé et des pratiques médicales, University of Lille, Lille, France.
J Epidemiol Community Health. 2025 Feb 10;79(3):200-206. doi: 10.1136/jech-2024-222704.
The incidence of lung cancer is unequally distributed in France. Although several studies have shown a link between the socioeconomic environment of populations and the incidence of cancer, the contribution has not been quantified. We aimed to analyse the geographical variability of lung cancer incidence in Normandy and calculate the proportion explained by the socioeconomic environment.
We included 7665 lung cancer cases recorded in the General Tumor Registry of Calvados and the Cancer Registry of Manche. A Bayesian model was used to map the spatial variation in the incidence of lung cancer in the territory, and an innovative approach was used to evaluate the influence of geographical variability in the socioeconomic environment on the spatial heterogeneity of lung cancer incidence.
The maps of the spatial components showed high contrasts for both genders, and the socioeconomic environment integration in the model made the maps less contrasting. The socioeconomic environment of the population explained one-third of the spatial variation in the incidence of lung cancer in women and one-fifth in men.
The results showed that a non-negligible part of the spatial variation in the incidence of lung cancer could be explained by the geographical distribution of the socioeconomic environment.
肺癌发病率在法国分布不均。尽管多项研究表明人群的社会经济环境与癌症发病率之间存在关联，但这种关联尚未得到量化。我们旨在分析诺曼底地区肺癌发病率的地理变异性，并计算社会经济环境所解释的比例。
我们纳入了在卡尔瓦多斯综合肿瘤登记处和芒什癌症登记处记录的7665例肺癌病例。采用贝叶斯模型绘制该地区肺癌发病率的空间变化图，并采用一种创新方法评估社会经济环境的地理变异性对肺癌发病率空间异质性的影响。
空间成分图显示男女两性的对比度都很高，模型中纳入社会经济环境后，地图的对比度降低。人群的社会经济环境解释了女性肺癌发病率空间变异的三分之一和男性的五分之一。
结果表明，肺癌发病率空间变异中不可忽视的一部分可由社会经济环境的地理分布来解释。
