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亚洲围产期人类免疫缺陷病毒研究:来自 TREAT Asia 网络的治疗结果和新兴合并症数据。

Research on Perinatal Human Immunodeficiency Virus in Asia: Data on Treatment Outcomes and Emerging Co-Morbidities from the TREAT Asia Network.

机构信息

Division of Infectious Diseases, Department of Pediatrics, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand; Clinical and Molecular Epidemiology of Emerging and Re-emerging Infectious Diseases Research Cluster, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.

Department of Pediatrics, BJ Government Medical College and Sassoon General Hospital, Pune, India.

出版信息

Clin Perinatol. 2024 Dec;51(4):911-923. doi: 10.1016/j.clp.2024.08.008. Epub 2024 Sep 10.

Abstract

Although new pediatric human immunodeficiency virus (HIV) infections have declined in the Asia-Pacific region, coverage of interventions to prevent vertical HIV transmission remains inconsistent. The TREAT Asia pediatric HIV cohort includes data from ∼7700 children and adolescents with HIV (90% perinatally acquired) who have been under care at 18 centers in six Asian countries. Research on their HIV treatment outcomes has been complemented by studies on coinfections and comorbidities. These studies have shown that greater attention is needed to support and sustain clinical and social outcomes as children with perinatal HIV age into adulthood and transition to adult HIV care.

摘要

尽管亚太地区新出现的儿科人类免疫缺陷病毒(HIV)感染有所减少,但预防垂直 HIV 传播的干预措施的覆盖范围仍然不一致。TREAT Asia 儿科 HIV 队列包括来自六个亚洲国家的 18 个中心的约 7700 名感染 HIV 的儿童和青少年(90%为围产期获得)的数据。对他们 HIV 治疗结果的研究得到了对合并感染和合并症的研究的补充。这些研究表明,随着围产期 HIV 感染的儿童成长为成年人并过渡到成人 HIV 护理,需要更加关注支持和维持临床和社会结果。

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