Department of Neurosciences, University of California, San Diego, 9500 Gilman Drive, #0935, La Jolla, CA 92093, USA.
Department of Psychiatry, Columbia University Vagelos College of Physicians and Surgeons, New York State Psychiatric Institute, 1051 Riverside Drive, Unit 15, New York, NY 10032, USA.
Clin Perinatol. 2024 Dec;51(4):865-879. doi: 10.1016/j.clp.2024.08.004. Epub 2024 Sep 20.
Perinatally acquired human immunodeficiency virus (HIV) has the potential to affect neurodevelopment and long-term cognitive and behavioral outcomes. Early, consistent viral suppression through antiretroviral therapy is a priority for protection of neurodevelopment. Monitoring of neurodevelopment and cognitive functioning, referral for appropriate interventions, caregiver/family support, and assessment of mental health, socioeconomic, and environmental risks are important to optimize health and well-being. Support for medication and health care adherence may be necessary to sustain best outcomes.
围产期获得的人类免疫缺陷病毒 (HIV) 有可能影响神经发育和长期的认知及行为结果。通过抗逆转录病毒疗法进行早期、持续的病毒抑制是保护神经发育的重点。监测神经发育和认知功能、提供适当干预的转介、照顾者/家庭支持,以及评估精神健康、社会经济和环境风险,对于优化健康和福祉非常重要。可能需要支持药物治疗和医疗保健依从性,以维持最佳结果。