中东和北非地区的肝癌与风险因素：基于 2019 年全球疾病负担数据的流行病学和时间趋势。
Liver Cancer and Risk Factors in the MENA Region: Epidemiology and Temporal Trends Based on the 2019 Global Burden of Disease Data.
机构信息
Department of Family Medicine, American University of Beirut Medical Center (AUBMC), Beirut, Lebanon.
Department of Internal Medicine, Hematology-Oncology, American University of Beirut (AUB), Beirut, Lebanon.
出版信息
Cancer Control. 2024 Jan-Dec;31:10732748241297346. doi: 10.1177/10732748241297346.
BACKGROUND
Liver cancer (LivCa) is a growing concern in the MENA region, driven by diverse factors, including viral hepatitis, lifestyle-related risks, and other causes.
METHODS
Utilizing GBD 2019 data, we assessed LivCa patterns, emphasizing chronic viral hepatitis, non-viral factors, and health care disparities across the MENA region.
RESULTS
Rising LivCa rates, particularly related to chronic viral hepatitis, highlight the region's health challenges. Lifestyle factors, such as obesity and diabetes, contribute significantly. Disparities in health care access and cancer registration hinder accurate assessments.
CONCLUSION
A comprehensive strategy is vital, encompassing vaccination promotion, health care enhancements, and lifestyle awareness. Urgent coordinated efforts are needed to address disparities, implement evidence-based interventions, and alleviate the escalating LivCa burden in the MENA region.
背景
在中东和北非地区，肝癌（LivCa）是一个日益严重的问题，这是由多种因素导致的，包括病毒性肝炎、与生活方式相关的风险以及其他原因。
方法
我们利用 GBD 2019 数据评估了中东和北非地区 LivCa 的模式，重点关注慢性病毒性肝炎、非病毒性因素以及卫生保健方面的差异。
结果
LivCa 发病率的上升，特别是与慢性病毒性肝炎相关的上升，凸显了该地区面临的健康挑战。生活方式因素，如肥胖和糖尿病，也起到了重要作用。卫生保健的可及性和癌症登记方面的差异妨碍了准确的评估。
结论
需要制定一项全面的策略，包括疫苗接种推广、加强卫生保健以及提高生活方式意识。需要紧急协调努力，以解决差异问题，实施基于证据的干预措施，并减轻中东和北非地区不断加剧的 LivCa 负担。
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