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[3-甲基胆蒽和莫洛尼氏鼠肉瘤病毒诱导的患肉瘤小鼠肌肉和肝脏中的脂肪酸含量]

[Fatty acid content in the muscles and liver of mice developing sarcomas induced by 3-methylcholanthrene and Moloney murine sarcoma virus].

作者信息

Grinevich Iu P, Bagleĭ E A, Ganich V G, Sidorik E P

出版信息

Eksp Onkol. 1986;8(1):44-7.

PMID:3948758
Abstract

A comparative analysis was made for the fatty acid composition of lipids in the malignant muscular tissue, muscle and liver under blastomogenesis induced in mice by the Moloney sarcoma virus and 3-methylcholanthrene. The relation of the found changes in the fatty acid composition to the blastomogenesis stages is shown. The development of the tumour node is accompanied by a decrease of the fatty acid amount in the animal tissues and by its increase in the tumour. A spontaneous regression of the Moloney sarcoma results in increased level of the fatty acid content in the animal tissues followed by its normalization.

摘要

对莫洛尼肉瘤病毒和3-甲基胆蒽诱导小鼠发生胚细胞瘤形成时,恶性肌肉组织、肌肉和肝脏中脂质的脂肪酸组成进行了比较分析。展示了所发现的脂肪酸组成变化与胚细胞瘤形成阶段的关系。肿瘤结节的发展伴随着动物组织中脂肪酸量的减少以及肿瘤中脂肪酸量的增加。莫洛尼肉瘤的自发消退导致动物组织中脂肪酸含量增加,随后恢复正常。

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