[3-甲基胆蒽和莫洛尼病毒诱导的肉瘤发育过程中小鼠组织中的分子电子载体]
[Molecular electron carriers in mouse tissues during development of sarcomas induced by 3-methylcholanthrene and Moloney virus].
作者信息
Sidorik E P, Grinevich Iu P, Mel'nikov O R, Bagleĭ E A
出版信息
Eksp Onkol. 1987;9(1):14-8.
Regular changes are revealed in electron-transport chains of the energy and detoxifying systems. The changes occur mainly in iron-sulphur centres and cytochrome P-450 under chemical and viral blastomogenesis in the muscular tissue induced by 3-methyl cholanthrene and Moloney oncornavirus. In the tissue of developing Moloney tumour and spleen kinetics of the formation of triplet signal of nitrosyl complexes is recorded in the region of g-factor of free radicals of semiquinone type and its transformation into singlet signal of EPR with the Moloney sarcoma regression.
能量和解毒系统的电子传递链中出现了规律性变化。这些变化主要发生在铁硫中心和细胞色素P - 450，是在由3 - 甲基胆蒽和莫洛尼氏肉瘤病毒诱导的肌肉组织化学和病毒致瘤过程中产生的。在发育中的莫洛尼氏肿瘤组织和脾脏中，在半醌型自由基g因子区域记录到亚硝酰络合物三重态信号的形成动力学，并且随着莫洛尼氏肉瘤消退，其转变为电子顺磁共振的单重态信号。
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