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使用小型和微型电离室评估离子复合和极性效应对光子深度剂量测量的影响。

Evaluation of ion recombination and polarity effect on photon depth dose measurements using mini- and micro-ion chamber.

作者信息

Fogliata Antonella, Bresolin Andrea, Gallo Pasqualina, La Fauci Francesco, Pelizzoli Marco, Reggiori Giacomo, Cozzi Luca

机构信息

Radiotherapy and Radiosurgery Dept, Humanitas IRCCS Research Hospital and Cancer Center, Milan-Rozzano, Italy.

出版信息

J Appl Clin Med Phys. 2025 Jan;26(1):e14495. doi: 10.1002/acm2.14495. Epub 2024 Nov 2.

Abstract

PURPOSE

To investigate the effect of ion recombination ( ) and polarity ( ) correction factors on percentage depth dose (PDD) curves for three ion chambers, using flat and flattening filter free (FFF) beams, across different broad field sizes. A method to assess these effects and their corresponding corrections is proposed.

METHODS

and were evaluated following the IAEA TRS-398 protocol for three ion chambers: PTW Semiflex-3D-31021, PinPoint-3D-31022, and Semiflex-31010. PDD measurements were acquired from d to 32 cm depth at four voltages (± 400 V or ± 300 V, and ± 100 V) for field sizes 4 × 4, 10 × 10, 20 × 20, and 40 × 40 cm. The values were computed after the correction at each applied voltage. This study aimed to assess the variation of the factors along scanning depths for different field sizes, to evaluate the need for correcting the scanning data.

RESULTS

was independent of depth and field size for Semiflex-3D, while it presented an increasing value with depth for the PinPoint-3D. increased with dose rate, i.e., decreased with depth. The variation of this perturbation effect over the PDD range was about 0.1% for flat beams with all three ion chambers. With FFF beams, it was around 0.3% with PinPoint-3D, and 0.8% for 10FFF with Semiflex-3D. A second-order polynomial fit can be determined to directly correct the raw data scanned along the beam axis for both and .

CONCLUSION

can significantly affect the PDD scanning measurements in FFF beams acquired with Semiflex-3D. An error close to 1% at large depths could be present, meaning an error of less than 0.3% relative to the dose at the depth of d.

摘要

目的

研究离子复合( )和极性( )校正因子对三种电离室在使用扁平和平坦滤过自由(FFF)射束、不同大野尺寸情况下的百分深度剂量(PDD)曲线的影响。提出一种评估这些影响及其相应校正的方法。

方法

按照国际原子能机构TRS - 398协议对三种电离室进行评估:PTW半柔性3D - 31021、针点3D - 31022和半柔性31010。在四种电压(±400 V或±300 V以及±100 V)下,针对4×4、10×10、20×20和40×40 cm的射野尺寸,从深度d到32 cm获取PDD测量值。在每个施加电压下进行 校正后计算 值。本研究旨在评估不同射野尺寸下这些因子沿扫描深度的变化,以评估校正扫描数据的必要性。

结果

对于半柔性3D, 与深度和射野尺寸无关,而对于针点3D,其值随深度增加。 随剂量率增加,即随深度减小。对于所有三种电离室的扁平射束,这种扰动效应在PDD范围内的变化约为0.1%。对于FFF射束,针点3D约为0.3%,半柔性3D的10FFF为0.8%。可以确定二阶多项式拟合以直接校正沿射束轴扫描的原始数据的 和 。

结论

可显著影响使用半柔性3D获取的FFF射束中的PDD扫描测量。在大深度处可能存在接近1%的误差,相对于深度d处的剂量而言误差小于0.3%。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2657/11712343/371714785684/ACM2-26-e14495-g003.jpg

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