Hiraoka Takahiro, Tamura Masato, Mino Toshihiro, Moriguchi Yoshikiyo, Akiba Masahiro, Sugiura Yoshimi, Mihashi Toshifumi, Oshika Tetsuro
Institute of Medicine, Department of Ophthalmology, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba, Ibaraki, 305-8575, Japan.
Research and Development Division, Topcon Corporation, Tokyo, Japan.
Jpn J Ophthalmol. 2025 Jan;69(1):24-31. doi: 10.1007/s10384-024-01128-5. Epub 2024 Nov 2.
This study aimed to investigate the choroidal thickness (ChT) distribution in adult myopic eyes, focusing on the macular, nasal midperiphery, and temporal midperiphery regions, and to explore its relationship with axial length (AL) and refractive error.
A cross-sectional, observational study.
Twenty-nine eyes of 29 adult volunteers were examined. ChT was measured using high-speed swept-source optical coherence tomography covering an area of 50 degrees in three different regions: centered at macular, nasal side at 33 degrees, and temporal side at 33 degrees. Statistical analyses were performed to assess differences in ChT between regions and correlations with AL and spherical equivalent (SE).
ChT was found to be thickest in the macular region, followed by the nasal and temporal midperiphery regions. Significant correlations were observed between AL/SE and ChT in the macular and temporal regions, but not in the nasal region. The temporal midperiphery showed the strongest correlation with AL and SE.
This study revealed a nasal-temporal asymmetry in ChT distribution in myopic eyes, with the temporal midperiphery showing the thinnest ChT. The strong correlations between ChT in the temporal midperiphery and AL/SE suggest a role for the temporal choroid in axial elongation and myopia progression. These findings highlight the importance of considering peripheral ChT in understanding ocular growth and myopia management.
本研究旨在调查成年近视眼中脉络膜厚度（ChT）的分布情况，重点关注黄斑区、鼻侧中周边部和颞侧中周边部区域，并探讨其与眼轴长度（AL）和屈光不正的关系。
一项横断面观察性研究。
对29名成年志愿者的29只眼睛进行了检查。使用高速扫频光学相干断层扫描测量ChT，扫描范围覆盖三个不同区域的50度范围：以黄斑为中心、鼻侧33度处和颞侧33度处。进行统计分析以评估各区域之间ChT的差异以及与AL和等效球镜度（SE）的相关性。
发现ChT在黄斑区最厚，其次是鼻侧和颞侧中周边部区域。在黄斑区和颞侧区域观察到AL/SE与ChT之间存在显著相关性，但在鼻侧区域未观察到。颞侧中周边部与AL和SE的相关性最强。
本研究揭示了近视眼中ChT分布的鼻颞侧不对称性，颞侧中周边部的ChT最薄。颞侧中周边部的ChT与AL/SE之间的强相关性表明颞侧脉络膜在眼轴延长和近视进展中起作用。这些发现突出了在理解眼部生长和近视管理中考虑周边ChT的重要性。
