Pezzoli Patrizia, Pingault Jean-Baptiste, Eley Thalia C, McCrory Eamon, Viding Essi
Division of Psychology and Language Sciences, University College London (UCL), London, UK.
Social, Genetic & Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.
Mol Psychiatry. 2025 May;30(5):2027-2037. doi: 10.1038/s41380-024-02813-0. Epub 2024 Nov 2.
Childhood maltreatment and intimate partner violence (IPV) victimization are major psychiatric risk factors. Maltreatment substantially increases the likelihood of subsequent IPV victimization, but what drives this association is poorly understood. We analyzed retrospective self-reports of maltreatment and IPV victimization in 12,794 participants (58% women, 42% men) from the Twins Early Development Study at ages 21 and 26 using quantitative genetic methods. We estimated the etiological influences common to maltreatment and IPV, and the effect of maltreatment on IPV beyond such common influences. Participants who reported childhood maltreatment ( ~ 7% of the sample) were 3 times more likely than their peers to also report IPV victimization at age 21, 4 times more likely at 26. The association between maltreatment and IPV was mostly due to environmental influences shared by co-twins (42-43%) and genetic influences (30-33%), as well as nonshared environmental influences (25-27%). The association between maltreatment and IPV was similar for women and men, but its etiology partly differed by sex. Maltreatment had a moderate effect on IPV in phenotypic models (β = 0.25-0.30), decreasing to a small-to-moderate range in causally informative models accounting for their common etiology (β = 0.15-0.21). Risk factors common to maltreatment and IPV victimization are largely familial in origin, environmental and genetic. Even considering common risk factors, experiencing maltreatment may be causally related to subsequent IPV victimization. Interventions promoting safe intimate relationships among young adults exposed to maltreatment are warranted and should address family-level environmental risk and individual-level risk shaped by genetics.
童年期受虐和亲密伴侣暴力受害经历是主要的精神疾病风险因素。受虐会大幅增加后续亲密伴侣暴力受害的可能性,但这种关联背后的驱动因素却鲜为人知。我们使用定量遗传学方法,分析了来自双胞胎早期发育研究的12794名参与者(58%为女性,42%为男性)在21岁和26岁时关于受虐和亲密伴侣暴力受害经历的回顾性自我报告。我们估计了受虐和亲密伴侣暴力受害经历共有的病因学影响,以及受虐对亲密伴侣暴力受害经历超出此类共同影响的作用。报告有童年期受虐经历的参与者(约占样本的7%)在21岁时报告亲密伴侣暴力受害经历的可能性是同龄人中的3倍,在26岁时是4倍。受虐与亲密伴侣暴力受害经历之间的关联主要归因于双胞胎共同拥有的环境影响(42%-43%)、遗传影响(30%-33%)以及非共享环境影响(25%-27%)。受虐与亲密伴侣暴力受害经历之间的关联在男性和女性中相似,但其病因在性别上存在部分差异。在表型模型中,受虐对亲密伴侣暴力受害经历有中等程度的影响(β = 0.25 - 0.30),在考虑其共同病因的因果信息模型中,影响程度降至小到中等范围(β = 0.15 - 0.21)。受虐和亲密伴侣暴力受害经历共有的风险因素在很大程度上源于家庭,包括环境和遗传因素。即使考虑到共同的风险因素,童年期受虐经历仍可能与后续亲密伴侣暴力受害经历存在因果关系。有必要对曾遭受虐待的年轻人开展促进安全亲密关系的干预措施,这些措施应针对家庭层面的环境风险以及由遗传因素塑造的个体层面风险。