Bishop Scott, Dech Ryan, Baker Taylor, Butz Matthew, Aravinthan Kaishan, Neary J Patrick
a Faculty of Kinesiology and Health Studies , University of Regina , Regina , Saskatchewan , Canada.
b College of Medicine , University of Saskatchewan , Saskatoon , Saskatchewan , Canada.
Brain Inj. 2017;31(2):247-259. doi: 10.1080/02699052.2016.1226385. Epub 2017 Jan 3.
To assess and compare the parasympathetic state of individuals in healthy vs concussion groups, by measuring cardiovascular metrics under resting and baroreflex conditions using a squat-stand manoeuvre.
This was a retrospective mixed-method study, with participants who sustained a medically diagnosed sport concussion (n = 12), being tested within 72-hours post-injury.
Participant's heart rate (Electrocardiogram, ECG) and blood pressure (finger plethysmography) data was collected during rest and during 10-second squat-stands (10SS, 0.05 Hz). Blood pressure and heart rate standard deviation data was analysed in the 0-5 seconds and 6-10 seconds periods of squatting and standing. Resting and baroreflex ECG data were analysed via Fourier Transformations for %Low Frequency and %High Frequency (%LF and %HF).
The control group alleviated more pressure and had a significantly higher standard deviation of heart rate during the 6-10 seconds of squatting (p < 0.05). Overall heart rate standard deviation in the concussion group was significantly lower than healthy controls when standing (p < 0.05). There were no differences in %LF and % HF between groups or between rest and 10SS.
This study provides preliminary evidence that autonomic function is dysregulated following mTBI within the initial 72 hours of injury.
通过使用深蹲-站立动作在静息和压力反射条件下测量心血管指标，评估和比较健康组与脑震荡组个体的副交感神经状态。
这是一项回顾性混合方法研究，研究对象为经医学诊断为运动性脑震荡的参与者（n = 12），在受伤后72小时内进行测试。
在静息状态和10秒深蹲-站立（10SS，0.05赫兹）过程中收集参与者的心率（心电图，ECG）和血压（手指容积描记法）数据。在深蹲和站立的0 - 5秒和6 - 10秒期间分析血压和心率标准差数据。通过傅里叶变换分析静息和压力反射心电图数据的低频百分比和高频百分比（%LF和%HF）。
对照组在深蹲6 - 10秒期间缓解了更多压力，心率标准差显著更高（p < 0.05）。脑震荡组站立时的总体心率标准差显著低于健康对照组（p < 0.05）。两组之间以及静息和10SS之间的%LF和%HF没有差异。
本研究提供了初步证据，表明在轻度创伤性脑损伤后的最初72小时内自主神经功能失调。
