CAD-PsorNet: deep transfer learning for computer-assisted diagnosis of skin psoriasis.

Psoriasis, being a chronic, inflammatory, lifelong skin disorder, has become a major threat to the human population. The precise and effective diagnosis of psoriasis continues to be difficult for clinicians due to its varied nature. In northern India, the prevalence of psoriasis among adult population ranges from 0.44 to 2.8%. Chronic plaque psoriasis accounts for over 90% of cases. This study utilized a dataset of 325 raw images collected from a reputable local hospital using a digital camera under uniform lighting conditions. These images were processed to generate 496 image patches (both diseased and normal), which were then normalized and resized for model training. An automated psoriasis image recognition framework was developed using four state-of-the-art deep transfer learning models: VGG16, VGG19, MobileNetV1, and ResNet-50. The convolutional layers adopted various edge, shape, and color filters to generate the feature map for psoriasis detection. Each pre-trained model was adapted with two dense layers, one dropout layer, and one output layer to classify input images. Among these models, MobileNetV1 achieved the best performance, with 94.84% sensitivity, 89.37% specificity, and 97.24% overall accuracy. Hyper-parameter tuning was performed using grid search to optimize learning rates, batch sizes, and dropout rates. The AdaGrad (Adaptive gradient)) optimizer was chosen for its adaptive learning rate capabilities, facilitating quicker convergence in model performance. Consequently, the methodology's performance improved to 94.25% sensitivity, 96.42% specificity, and 99.13% overall accuracy. The model's performance was also compared with non-machine learning-based diagnostic methods, yielding a Dice coefficient of 0.98. However, the model's effectiveness is dependent upon high-quality input images, as poor image conditions may affect accuracy, and it may not generalize well across diverse demographics or psoriasis variations, highlighting the need for varied training datasets for robustness.