Säwe U, Erhardt L R, Sjögren A
Acta Med Scand. 1976;199(3):217-21. doi: 10.1111/j.0954-6820.1976.tb06719.x.
The present study on 55 consecutive patients with acute myocardial infarction (AMI) draws attention to the relationship between different enzyme maxima in AMI, with special reference to serum gamma-glutamyl transpeptidase (S-GT). In more than 60% of the patients the S-GT was increased during the hospital stay. The S-GT rise nearly always began during the first days, reached a maximum within 5--8 days and normalized with 2--3 weeks. We failed to find the late increase in S-GT reported by others. The rise of S-GT is particularly common in patients with inferior infarction, with or without right ventricular involvement. We conclude that S-GT activity is not a useful early or late indicator of AMI but a very sensitive test for hepatic dysfunction in patients with AMI.
本项针对55例连续急性心肌梗死（AMI）患者的研究，关注了AMI中不同酶峰值之间的关系，特别提及血清γ-谷氨酰转肽酶（S-GT）。超过60%的患者在住院期间S-GT升高。S-GT升高几乎总是在最初几天开始，在5 - 8天内达到峰值，并在2 - 3周内恢复正常。我们未发现其他人报道的S-GT后期升高情况。S-GT升高在伴有或不伴有右心室受累的下壁梗死患者中尤为常见。我们得出结论，S-GT活性并非AMI有用的早期或晚期指标，而是AMI患者肝功能障碍的一项非常敏感的检测指标。
