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鞘内疼痛泵靶向药物递送治疗恶性疼痛。

Targeted drug delivery via intrathecal pain pump for the treatment of malignant pain.

机构信息

University of Colorado, Department of Radiology Interventional Radiology Section, Aurora, CO.

Radiology Alliance Director of Radiology Summit Hospital, Hermitage, TN.

出版信息

Tech Vasc Interv Radiol. 2024 Sep;27(3):100985. doi: 10.1016/j.tvir.2024.100985. Epub 2024 Aug 24.

Abstract

Cancer patients experience pain at significant rates but are often undertreated-it is estimated that less than 1% of eligible cancer pain patients receive appropriate targeted drug delivery to address their pain. Cancer pain is often managed with systemic opioid treatment; however, this approach is limited in treating pain adequately and carries significant side effect risk profiles. Successful treatment of pain is closely tied to better oncologic outcomes as well as better measures on assessments of quality of life for cancer patients. Placement of intrathecal pain pumps represent a safe and effective way to manage pain in cancer patients. We describe the process of placing intrathecal pain pumps in an interventional radiology suite. This method of pump placement represents a minimally invasive approach to long term and continuous pain relief. Intrathecal pain pumps help maximize pain control for patients experiencing refractory pain due to disease process or treatments associated with malignancy.

摘要

癌症患者经历疼痛的比例很高,但往往治疗不足——据估计,只有不到 1%的符合条件的癌症疼痛患者接受了适当的靶向药物治疗来缓解疼痛。癌症疼痛通常通过全身阿片类药物治疗来管理;然而,这种方法在充分治疗疼痛方面存在局限性,并且具有显著的副作用风险特征。疼痛的成功治疗与更好的肿瘤学结果以及更好的癌症患者生活质量评估措施密切相关。植入鞘内疼痛泵是管理癌症患者疼痛的一种安全有效的方法。我们描述了在介入放射学套房中放置鞘内疼痛泵的过程。这种泵放置方法是一种微创的长期持续缓解疼痛的方法。鞘内疼痛泵有助于最大限度地控制因疾病过程或与恶性肿瘤相关的治疗而导致难治性疼痛的患者的疼痛。

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