Yan Hua
Department of Biology, University of Florida, Gainesville, FL 32611, USA; Center for Smell and Taste, University of Florida, Gainesville, FL 32610, USA.
Curr Opin Insect Sci. 2025 Feb;67:101288. doi: 10.1016/j.cois.2024.101288. Epub 2024 Oct 25.
Insects represent the most diverse group of animals in the world. While the olfactory systems of different species share general principles of organization, they also exhibit a wide range of structural and functional diversity. Scientists have gained tremendous insight into olfactory neural development and function, notably in Drosophila, but also in other insect species (see reviews by Benton, 2022; Robertson, 2019; Yan et al., 2020). In the last few years, new evidence has steadily mounted, for example, the stoichiometry of odorant receptor and co-receptor (OR-Orco) complex. This review aims to highlight the recent progress on four aspects: (1) the structure and function of the OR-Orco complex, (2) chemosensory gene co-expression, (3) diverse neural developmental processes, and (4) the role of genes and neurons in olfactory development and olfactory-mediated behavior.
昆虫是世界上种类最多样化的动物群体。虽然不同物种的嗅觉系统具有共同的组织原则，但它们也表现出广泛的结构和功能多样性。科学家们对嗅觉神经发育和功能有了深入了解，尤其是在果蝇中，但在其他昆虫物种中也有研究（见Benton，2022；Robertson，2019；Yan等人，2020年的综述）。在过去几年中，新的证据不断涌现，例如气味受体和共同受体（OR-Orco）复合物的化学计量学。本综述旨在突出四个方面的最新进展：（1）OR-Orco复合物的结构和功能，（2）化学感应基因共表达，（3）多样的神经发育过程，以及（4）基因和神经元在嗅觉发育和嗅觉介导行为中的作用。
