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晶状体置换术:旨在保留调节功能的白内障手术。

Phaco-Ersatz: cataract surgery designed to preserve accommodation.

作者信息

Parel J M, Gelender H, Trefers W F, Norton E W

出版信息

Graefes Arch Clin Exp Ophthalmol. 1986;224(2):165-73. doi: 10.1007/BF02141492.

DOI:10.1007/BF02141492
PMID:3949191
Abstract

Phaco-Ersatz represents a new approach to cataract surgery and the correction of aphakia. The procedure involves the removal of the cataractous cortex and nucleus while preserving the lens capsule and its zonular attachments. The empty lens capsule is then refilled with biocompatible and optically suitable clear gel. A physiologic lens is recreated in situ. Experimental work with human cadaver eyes and rabbit and cat eyes in vivo demonstrates this surgical feasibility. A review of the literature reveals contradicting theories regarding the physical laws and lens properties governing accommodation. The accommodative potential of the ersatz lens has not been tested, but it may be speculated that this recreated lens may, in fact, possess some accommodative properties. Experimental investigations in this area represent the logical extension of intraocular lens implant development.

摘要

超声乳化替代术是一种治疗白内障手术及无晶状体矫正的新方法。该手术包括切除白内障皮质和核,同时保留晶状体囊及其小带附着。然后将空的晶状体囊用生物相容性好且光学性能合适的透明凝胶重新填充。在原位重建一个生理性晶状体。对人体尸体眼以及兔眼和猫眼进行的体内实验工作证明了这种手术的可行性。文献综述揭示了关于调节所涉及的物理定律和晶状体特性存在相互矛盾的理论。替代晶状体的调节潜力尚未经过测试,但可以推测这种重建的晶状体实际上可能具有一些调节特性。该领域的实验研究是人工晶状体植入发展的合理延伸。

相似文献

1
Phaco-Ersatz: cataract surgery designed to preserve accommodation.晶状体置换术:旨在保留调节功能的白内障手术。
Graefes Arch Clin Exp Ophthalmol. 1986;224(2):165-73. doi: 10.1007/BF02141492.
2
Accommodation of an endocapsular silicone lens (Phaco-Ersatz) in the nonhuman primate.非人类灵长类动物体内囊内硅胶晶状体(超声乳化替代物)的适应性。
Ophthalmology. 1987 May;94(5):471-7. doi: 10.1016/s0161-6420(87)33422-0.
3
Refilling the lens with a inflatable endocapsular balloon: surgical procedure in animal eyes.用可充气的囊内球囊重新填充晶状体:动物眼部手术操作
Graefes Arch Clin Exp Ophthalmol. 1992;230(1):47-55. doi: 10.1007/BF00166762.
4
Theoretical analysis of accommodation amplitude and ametropia correction by varying refractive index in Phaco-Ersatz.白内障超声乳化手术替代技术中通过改变折射率进行调节幅度和屈光不正矫正的理论分析
Optom Vis Sci. 2001 Jun;78(6):405-10. doi: 10.1097/00006324-200106000-00012.
5
Lens refilling and endocapsular polymerization of an injectable intraocular lens: in vitro and in vivo study of potential risks and benefits.可注射人工晶状体的晶状体再填充及囊内聚合:潜在风险与益处的体外及体内研究
J Cataract Refract Surg. 1994 Mar;20(2):115-23. doi: 10.1016/s0886-3350(13)80149-6.
6
Functionalised polysiloxanes as injectable, in situ curable accommodating intraocular lenses.功能化聚硅氧烷作为可注射、原位固化的适应性眼内透镜。
Biomaterials. 2010 Nov;31(32):8153-63. doi: 10.1016/j.biomaterials.2010.07.065. Epub 2010 Aug 7.
7
Amplitudes of accommodation of primate lenses refilled with two types of inflatable endocapsular balloons.用两种类型的可充气囊内球囊重新填充的灵长类动物晶状体的调节幅度。
Arch Ophthalmol. 1993 Dec;111(12):1677-84. doi: 10.1001/archopht.1993.01090120099029.
8
Accommodative intraocular lens with spring action--Part 2. Fixation in the living rabbit.具有弹簧作用的调节性人工晶状体——第2部分。在活兔眼中的固定
Ophthalmic Surg. 1992 Sep;23(9):632-5.
9
Complications associated with endocapsular balloon implantation in rabbit eyes.
J Cataract Refract Surg. 1994 Sep;20(5):507-12. doi: 10.1016/s0886-3350(13)80229-5.
10
Epilenticular intraocular lens implantation in traumatic cataract with a ruptured posterior capsule.外伤性白内障合并后囊破裂的晶状体后房型人工晶状体植入术
Am J Ophthalmol. 2000 Sep;130(3):352-3. doi: 10.1016/s0002-9394(00)00551-1.

引用本文的文献

1
Advances in the Study of Lens Refilling.晶状体再填充研究进展
J Ophthalmol. 2020 Aug 26;2020:8956275. doi: 10.1155/2020/8956275. eCollection 2020.
2
Age-Related Changes to the Three-Dimensional Full Shape of the Isolated Human Crystalline Lens.年龄相关性对人眼晶状体三维全形态的改变。
Invest Ophthalmol Vis Sci. 2020 Apr 9;61(4):11. doi: 10.1167/iovs.61.4.11.
3
The lens growth process.晶状体生长过程。

本文引用的文献

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The Response of the Lens Capsules in the Act of Accommodation.晶状体囊在调节过程中的反应。
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EXPERIMENTS IN REFILLING THE LENS.晶状体再填充实验
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[Sealing of conjunctival fistulas by means of a fibrinogen adhesive (author's transl)].用纤维蛋白原粘合剂封闭结膜瘘(作者译)
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Translating ocular biomechanics into clinical practice: current state and future prospects.将眼生物力学转化为临床实践:现状与未来前景。
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Contribution of the crystalline lens gradient refractive index to the accommodation amplitude in non-human primates: in vitro studies.晶状体梯度折射率对非人灵长类动物调节幅度的贡献:体外研究
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Age-dependence of the optomechanical responses of ex vivo human lenses from India and the USA, and the force required to produce these in a lens stretcher: the similarity to in vivo disaccommodation.来自印度和美国的离体人晶状体光机械反应的年龄依赖性,以及在晶状体拉伸器中产生这些反应所需的力:与体内调节减退的相似性。
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Functionalised polysiloxanes as injectable, in situ curable accommodating intraocular lenses.功能化聚硅氧烷作为可注射、原位固化的适应性眼内透镜。
Biomaterials. 2010 Nov;31(32):8153-63. doi: 10.1016/j.biomaterials.2010.07.065. Epub 2010 Aug 7.
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4
Intraocular lenses.人工晶状体
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The message of a bony lens.骨透镜的信息。
Ophthalmic Surg. 1981 May;12(5):332-5.
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A photographic study of accommodative mechanisms: changes in the lens nucleus during accommodation.调节机制的摄影研究:调节过程中晶状体核的变化。
Invest Ophthalmol. 1967 Dec;6(6):601-11.
7
Refilling the rabbit lens. Further experiments.给兔眼晶状体重新注液。进一步的实验。
Arch Ophthalmol. 1966 Oct;76(4):596-8. doi: 10.1001/archopht.1966.03850010598021.
8
A thin shell deformation analysis of the human lens.
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Unified model for accommodative mechanism.
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The change in shape and internal form of the lens of the eye on accommodation.眼睛晶状体在调节时形状和内部形态的变化。
Exp Eye Res. 1973 Apr;15(4):441-59. doi: 10.1016/0014-4835(73)90136-x.