Haefliger E, Parel J M, Fantes F, Norton E W, Anderson D R, Forster R K, Hernandez E, Feuer W J
Ophthalmology. 1987 May;94(5):471-7. doi: 10.1016/s0161-6420(87)33422-0.
In owl monkeys, as a model of endocapsular cataract extraction, the lens material was removed through a small hole in the capsule and was replaced with a silicone polymeric gel. The ability of this endocapsular implant (Phaco-Ersatz) to accommodate was documented when pilocarpine produced an increase in the curvature of the lens surface and a decrease in the anterior chamber depth, just as occurs with the untouched natural lens. Refinements of the surgical technique are required to achieve a controlled degree of filling of the capsular bag and inhibit postoperative epithelial proliferation on the inner capsular surface.
在作为囊内白内障摘除模型的夜猴中，晶状体物质通过囊膜上的一个小孔被移除，并用硅聚合物凝胶替代。当毛果芸香碱使晶状体表面曲率增加、前房深度减小时，就如同未受影响的天然晶状体那样，这种囊内植入物（超声乳化替代物）的调节能力得到了证实。需要改进手术技术，以实现对囊袋填充程度的控制，并抑制术后囊膜内表面上皮细胞的增殖。
