Kalra Yash, Koppolu Saahiti, Babu Manu, Prashant Rashmi, Raj Akshi, Ingale Mayur
Department of Otolaryngology, Head and Neck Surgery, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Dr. D. Y. Patil Vidyapeeth (Deemed to be University), Pune, IND.
Department of Pathology, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Dr. D. Y. Patil Vidyapeeth (Deemed to be University), Pune, IND.
Cureus. 2024 Oct 3;16(10):e70746. doi: 10.7759/cureus.70746. eCollection 2024 Oct.
This report describes an uncommon tumor of the salivary glands, myoepithelioma, that primarily affects major and minor glands, with a notable predilection for the parotid gland. Typically benign, this tumor arises from aberrant myoepithelial cells situated between the basement membrane and acinar cells. Myoepitheliomas are considered a subset of pleomorphic adenomas, distinguished by excessive myoepithelial cell growth. Despite their initial discovery, the precise histopathological and immunohistochemical characteristics of these tumors remain elusive, posing a diagnostic challenge because of their complex nature. We discuss a case of a 42-year-old female who had a 2 x 2 cm lump in the right infra-auricular area. The lump was examined with ultrasonography (USG) and later surgically removed. The initial frozen section analysis indicated an oncocytic lesion, but further histopathological and immunohistochemical evaluations confirmed that it was a myoepithelioma of the parotid gland.
本报告描述了一种罕见的唾液腺肿瘤——肌上皮瘤,它主要累及大唾液腺和小唾液腺,尤其好发于腮腺。该肿瘤通常为良性,由位于基底膜和腺泡细胞之间的异常肌上皮细胞产生。肌上皮瘤被认为是多形性腺瘤的一个亚型,其特征是肌上皮细胞过度生长。尽管它们已被首次发现,但这些肿瘤确切的组织病理学和免疫组化特征仍不明确,因其性质复杂而带来诊断挑战。我们讨论一例42岁女性病例,她在右耳下区域有一个2×2厘米的肿块。对该肿块进行了超声检查(USG),随后手术切除。最初的冰冻切片分析显示为嗜酸细胞性病变,但进一步的组织病理学和免疫组化评估证实它是腮腺肌上皮瘤。