Sethi Divya, Ahluvalia Charanjeet, Khatri Arti, Khetarpal Sheena
Department of Pathology, VMMC and Safdarjang Hospital, Delhi, India.
Adv Biomed Res. 2012;1:78. doi: 10.4103/2277-9175.102985. Epub 2012 Oct 31.
Myoepitheliomas are benign neoplasms of salivary glands derived from myoepithelial cells. These tumors can occur at any age but are most common in young adults. This tumor is usually located in the parotid gland and the minor salivary glands of the soft palate and represents less than 1% of all salivary gland tumors. The myoepithelioma is classified in the follow cells types: spindle, plasmacytoid, reticular, epitheliod, and clear, additionally, mixed histological forms are described. The plasmacytoid myoepithelioma from palate salivary glands is considered as a rare entity. A 45-year-old lady presented with an asymptomatic, well-circumscribed, solid mass located on the hard palate, which was gradually increasing in size. A clinical impression of Pleomorphic Adenoma was made which on histopathological examination revealed cords, clusters, and sheets of homogenous, large cells with plasmacytoid characteristics and a prominent eosinophilic cytoplasm. Ductal and acinar differentiation were absent thus ruling out the pleomorphic adenoma, whereas, features consistent with plasmacytoid myoepithelioma were evident.
肌上皮瘤是起源于肌上皮细胞的唾液腺良性肿瘤。这些肿瘤可发生于任何年龄，但在年轻人中最为常见。该肿瘤通常位于腮腺以及软腭的小唾液腺，占所有唾液腺肿瘤的比例不到1%。肌上皮瘤可分为以下细胞类型：梭形、浆细胞样、网状、上皮样和透明样，此外，还描述了混合组织学形式。腭部唾液腺的浆细胞样肌上皮瘤被认为是一种罕见的实体。一位45岁女性患者，硬腭出现一个无症状、边界清晰的实性肿块，且肿块大小逐渐增大。临床初步诊断为多形性腺瘤，组织病理学检查显示有索状、团状和片状均匀的大细胞，具有浆细胞样特征和明显的嗜酸性细胞质。未见导管和腺泡分化，因此排除多形性腺瘤，而符合浆细胞样肌上皮瘤的特征明显。
