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一例在常规眼科诊疗中被忽视的东方眼幼虫(结膜吸吮线虫)感染病例

A Case of Larval Oriental Eye Worm, Thelazia callipaeda, Infection Overlooked in Routine Ophthalmic Practice.

作者信息

Uchida Naoki, Wada Yumare, Shimada Ayaka, Harano Akiko, Ichioka Sho, Otsuki Hitoshi, Tanito Masaki

机构信息

Department of Ophthalmology, Shimane University Faculty of Medicine, Izumo, JPN.

Division of Medical Zoology, Department of Microbiology and Immunology, Faculty of Medicine, Tottori University, Yonago, JPN.

出版信息

Cureus. 2024 Oct 2;16(10):e70717. doi: 10.7759/cureus.70717. eCollection 2024 Oct.

DOI:10.7759/cureus.70717
PMID:39493045
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11531319/
Abstract

, the oriental eyeworm, is a zoonotic parasite that primarily infects the eyes, causing symptoms such as foreign body sensation, tearing, and itching. It is transmitted by fruit flies like and commonly affects dogs and cats. This case report describes an 18-year-old woman who presented with complaints of "a worm in her left eye." Despite two visits to an ophthalmology clinic, she was initially diagnosed with conjunctivitis. The patient's history of dog ownership raised the possibility of zoonotic transmission; however, the worm was not detected during clinical examinations. Eventually, the patient removed the worm herself, and it was identified as the larval stage of . This case emphasizes the importance of considering in patients with nonspecific conjunctivitis symptoms, especially those with a history of contact with animals. It highlights the challenges in diagnosing this rare infection due to its nonspecific presentation and the small size of the larvae. Clinicians should be aware of this possibility and conduct thorough examinations, including double eversion of the eyelids, to avoid misdiagnosis and ensure appropriate treatment.

摘要

结膜吸吮线虫是一种人畜共患寄生虫,主要感染眼睛,引起异物感、流泪和瘙痒等症状。它通过如 等果蝇传播,通常感染狗和猫。本病例报告描述了一名18岁女性,她主诉“左眼有一条虫子”。尽管她两次前往眼科诊所就诊,但最初被诊断为结膜炎。患者养狗的病史增加了人畜共患传播的可能性;然而,临床检查期间未检测到虫子。最终,患者自行取出了虫子,经鉴定为结膜吸吮线虫的幼虫阶段。本病例强调了在有非特异性结膜炎症状的患者中考虑结膜吸吮线虫感染的重要性,尤其是那些有动物接触史的患者。它突出了由于这种罕见感染的非特异性表现和幼虫体积小而导致诊断的挑战。临床医生应意识到这种可能性,并进行全面检查,包括眼睑双重翻转,以避免误诊并确保适当治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d09/11531319/582167e4c265/cureus-0016-00000070717-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d09/11531319/a0f55d44ba45/cureus-0016-00000070717-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d09/11531319/392ea2f793bc/cureus-0016-00000070717-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d09/11531319/582167e4c265/cureus-0016-00000070717-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d09/11531319/a0f55d44ba45/cureus-0016-00000070717-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d09/11531319/392ea2f793bc/cureus-0016-00000070717-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d09/11531319/582167e4c265/cureus-0016-00000070717-i03.jpg

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本文引用的文献

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Parasitol Int. 2024 Oct;102:102913. doi: 10.1016/j.parint.2024.102913. Epub 2024 Jun 15.
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Human ocular thelaziasis with genetic analysis in Niigata Prefecture, Japan: A case report on an emerging zoonosis.日本新潟县人类眼结膜吸吮线虫病及其基因分析:一例新发人畜共患病病例报告
Am J Ophthalmol Case Rep. 2024 Mar 9;34:102030. doi: 10.1016/j.ajoc.2024.102030. eCollection 2024 Jun.
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Thelazia callipaeda in Slovakia - From sporadic cases to endemic areas.
斯洛伐克的旋尾线虫病——从散发病例到流行地区。
Parasitol Int. 2022 Apr;87:102495. doi: 10.1016/j.parint.2021.102495. Epub 2021 Nov 2.
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Thelazia callipaeda infection during phacoemulsification cataract surgery: a case report.白内障超声乳化手术期间的结膜吸吮线虫感染:一例报告
BMC Ophthalmol. 2021 Oct 23;21(1):376. doi: 10.1186/s12886-021-02117-9.
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Thelaziosis due to Thelazia callipaeda in Europe in the 21st century-A review.二十一世纪欧洲犬首鞭形线虫性眼蝇蛆病——综述
Vet Parasitol. 2019 Nov;275:108957. doi: 10.1016/j.vetpar.2019.108957. Epub 2019 Oct 13.
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Thelazia eyeworm: an original endo- and ecto-parasitic nematode.吸吮线虫:一种独特的体内和体外寄生线虫。
Trends Parasitol. 2005 Jan;21(1):1-4. doi: 10.1016/j.pt.2004.10.008.
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Five cases of thelaziasis.五例吸吮线虫病。
Br J Ophthalmol. 2000 Apr;84(4):441. doi: 10.1136/bjo.84.4.439c.