Suppr超能文献

播散性伯氏淋巴细胞瘤病例报告,伴有狭义伯氏疏螺旋体在慢性淋巴细胞白血病Binet A期的分离——11年随访

Case report of disseminated borrelial lymphocytoma with isolation of sensu stricto in chronic lymphatic leukemia stage Binet A-an 11 year follow up.

作者信息

Hofmann Heidelore, Margos Gabriele, Todorova Antonia, Ringshausen Ingo, Kuleshov Konstantin, Fingerle Volker

机构信息

Department of Dermatology and Allergy, University Hospital Rechts der Isar, Technische Universität München, Munich, Germany.

National Reference Center for Borrelia, Bavarian Health and Food Safety Authority, Oberschleissheim, Germany.

出版信息

Front Med (Lausanne). 2024 Oct 18;11:1465630. doi: 10.3389/fmed.2024.1465630. eCollection 2024.

Abstract

We report a rare manifestation of cutaneous borreliosis in a patient with pre-existing malignant lymphoproliferative disease, in particular chronic lymphocytic B cell leukemia (B-CLL). The patient's cutaneous lesions were initially diagnosed histologically as leukemia cutis. Distribution pattern of the skin lesions were in typical localizations for borrelial lymphocytoma. sensu stricto was isolated and cultured from two sites (ear, mammilla). Antibiotic therapy improved the cutaneous lesions and the general condition of the patient. However, a second round of antibiotic therapy was required to resolve the lesions. At eleven years of follow-up the patient's skin was clear and she still had a stable condition of B-CLL without chemotherapy. In conclusion, the patient suffered from Lyme borreliosis ( lymphocytoma) and the cutaneous symptoms were aggravated by the underlying condition of chronic B-CLL condition.

摘要

我们报告了一例患有先前存在的恶性淋巴增殖性疾病,特别是慢性淋巴细胞性B细胞白血病(B-CLL)的患者出现皮肤型莱姆病的罕见表现。患者的皮肤病变最初经组织学诊断为皮肤白血病。皮肤病变的分布模式符合莱姆淋巴细胞瘤的典型定位。从两个部位(耳朵、乳头)分离并培养出了严格意义上的伯氏疏螺旋体。抗生素治疗改善了皮肤病变和患者的一般状况。然而,需要第二轮抗生素治疗才能使病变消退。在11年的随访中,患者的皮肤恢复正常,她的B-CLL病情稳定,无需化疗。总之,该患者患有莱姆病(淋巴细胞瘤),慢性B-CLL的基础疾病加重了皮肤症状。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ffbb/11527655/3423d5ce8251/fmed-11-1465630-g001.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验