Xu Xingxiu, Yang Nengyuan, Da Jingjing, Li Qian, Yuan Jing, Zha Yan
Renal Division, Department of Medicine, Guizhou Provincial People's Hospital, Guizhou Provincial Institute of Nephritic and Urinary Disease, Guiyang, China.
NHC Key Laboratory of Pulmonary Immunological Disease, Guizhou Provincial People's Hospital, Guiyang, China.
Front Med (Lausanne). 2024 Oct 18;11:1418075. doi: 10.3389/fmed.2024.1418075. eCollection 2024.
In China, diabetes mellitus (DM) significantly contributes to end-stage renal disease (ESRD), necessitating treatments like hemodialysis. This study investigates hemodialysis outcomes in diabetic nephropathy patients in Guizhou Province, aiming to enhance care for this high-risk group.
The cross-sectional survey design to screen haemodialysis patients with end-stage diabetic nephropathy, a structured questionnaire was designed. The collected data were collated and coded and analyzed using GraphPad Prism 9.5.0 (730).
Patients with end-stage diabetic nephropathy undergoing dialysis are primarily concentrated in the middle-aged and elderly population, with a higher proportion of males than females. Male patients also have a higher history of smoking and alcohol consumption compared to females. The disease progression from diabetes to diabetic nephropathy and from nephropathy to end-stage renal disease varies, with a lower dialysis vintage. Hemodialysis is the most commonly chosen treatment modality, with the highest proportion of patients selecting non-tunneled catheters. However, among patients receiving dialysis, the proportion of autogenous arteriovenous fistula (AVF) is the highest. With the increase in the duration of diabetes, the prevalence of multiple complications also increases.
Early intervention and management strategies are crucial for diabetic nephropathy patients in Guizhou, considering the rapid disease progression to ESRD and high complication rates. The study underscores the need for targeted healthcare policies to address the unique challenges of this population, with future research required to deepen the understanding of disease mechanisms and improve patient outcomes.
在中国，糖尿病（DM）是终末期肾病（ESRD）的重要病因，因此需要进行血液透析等治疗。本研究调查了贵州省糖尿病肾病患者的血液透析结果，旨在加强对这一高危群体的护理。
采用横断面调查设计筛选终末期糖尿病肾病血液透析患者，设计了结构化问卷。收集的数据进行整理、编码，并使用GraphPad Prism 9.5.0（730）进行分析。
接受透析的终末期糖尿病肾病患者主要集中在中老年人群，男性比例高于女性。男性患者的吸烟和饮酒史也高于女性。从糖尿病发展到糖尿病肾病以及从肾病发展到终末期肾病的病程各不相同，透析龄较短。血液透析是最常用的治疗方式，选择非隧道式导管的患者比例最高。然而，在接受透析的患者中，自体动静脉内瘘（AVF）的比例最高。随着糖尿病病程的增加，多种并发症的患病率也增加。
考虑到糖尿病肾病患者迅速发展为终末期肾病且并发症发生率高，早期干预和管理策略对贵州的糖尿病肾病患者至关重要。该研究强调需要制定针对性的医疗政策来应对这一人群的独特挑战，未来还需要进行研究以加深对疾病机制的理解并改善患者预后。
