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联合术前白蛋白-胆红素评分和肝切除百分比评估部分肝切除术后肝脏再生。

Combined preoperative albumin bilirubin score and hepatectomy percentage for evaluate the liver regeneration after partial hepatectomy.

机构信息

Department of Hepatobiliary Surgery, The Affiliated Drum Tower Hospital of Nanjing University of Chinese Medicine, Nanjing 210008, Jiangsu Province, China.

Division of Hepatobiliary and Transplantation Surgery, Department of General Surgery, Nanjing Drum Tower Hospital, Nanjing 210008, Jiangsu Province, China.

出版信息

World J Gastroenterol. 2024 Oct 28;30(40):4376-4379. doi: 10.3748/wjg.v30.i40.4376.

Abstract

Surgical resection is a pivotal therapeutic approach for addressing hepatic space-occupying lesions, with liver volume restoration and hepatic functional recovery being crucial for assessing surgical prognosis. The preoperative albumin-bilirubin (ALBI) score, encompassing serum albumin and bilirubin levels, can be determined via blood analysis, effectively mitigating human error and providing an accurate depiction of liver function. The hepatectomy ratio, which is the proportion of the liver volume removed to the total liver volume, is critical in preserving an adequate liver tissue volume to ensure postoperative hepatic functional compensation, minimize surgical complications, and reduce mortality rates. Incorporating the preoperative ALBI score and hepatectomy ratio aids surgeons in assessing the optimal timing and extent of partial hepatectomy. The introduction of preoperative albumin bilirubin score and hepatectomy percentage is beneficial for the surgeons to evaluate the timing and magnitude of partial liver resection.

摘要

手术切除是治疗肝脏占位性病变的关键治疗方法,肝体积恢复和肝功能恢复对于评估手术预后至关重要。术前白蛋白-胆红素(ALBI)评分通过血液分析确定,包含血清白蛋白和胆红素水平,可以有效降低人为误差并准确描述肝功能。肝切除率是切除的肝体积与总肝体积的比例,对于保留足够的肝组织体积以确保术后肝功能代偿、最小化手术并发症和降低死亡率至关重要。术前 ALBI 评分和肝切除率的结合有助于外科医生评估部分肝切除术的最佳时机和范围。引入术前白蛋白胆红素评分和肝切除百分比有助于外科医生评估部分肝切除的时机和程度。

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Cell Plasticity in Liver Regeneration.肝再生中的细胞可塑性。
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