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子宫肌瘤切除术中意外早期妊娠并足月成功分娩:一例报告

Unexpected early pregnancy during myomectomy followed by successful term delivery: A case report.

作者信息

Saharkhiz Nasrin, Nemati Mitra, Hajizadeh Nazanin, Abbasi Hajar

机构信息

Preventative Gynecology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

出版信息

Int J Reprod Biomed. 2024 Oct 14;22(8):673-678. doi: 10.18502/ijrm.v22i8.17242. eCollection 2024 Aug.

DOI:10.18502/ijrm.v22i8.17242
PMID:39494124
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11528293/
Abstract

BACKGROUND

Leiomyoma, also known as uterine fibroid, is a non-malignant tumor originating from the uterus's smooth muscles. It is the most common benign tumor in the female genital tract, exhibiting varying size and form that can distort the uterus's shape. Uterine fibroids affect 2.7-10.7% of pregnant women and can lead to increased risks during pregnancy, such as miscarriage, placental abruption, preterm labor, and fetal malpresentation. Myomectomy is a surgical intervention for uterine fibroids, but it has drawbacks, including hemorrhage, fever, infection, ureter ligation, adhesive disorders, and unplanned hysterectomy.

CASE PRESENTATION

In this case report, we present a 32-yr-old woman with a large leiomyoma who underwent laparotomy myomectomy due to abdominal pain and heavy menstrual bleeding. 4 wk after the myomectomy, she was referred to the Obstetric Clinic of Ayatollah Taleghani hospital, Tehran, Iran complaining of delayed menstruation. Her beta-human chorionic gonadotropin test was positive. Ultrasound revealed a fetus with an estimated gestational age of 6 wk and 4 days. The pregnancy continued with no complications. At 38 wk of gestation, she underwent a cesarean section and delivered a healthy newborn.

CONCLUSION

This case report supports previous publications that have demonstrated the safety of myomectomy during pregnancy.

摘要

背景

平滑肌瘤,又称子宫肌瘤,是一种起源于子宫平滑肌的非恶性肿瘤。它是女性生殖道最常见的良性肿瘤,大小和形态各异,可使子宫形态扭曲。子宫肌瘤影响2.7%至10.7%的孕妇,并可导致孕期风险增加,如流产、胎盘早剥、早产和胎位异常。子宫肌瘤切除术是治疗子宫肌瘤的一种手术干预方法,但它有一些缺点,包括出血、发热、感染、输尿管结扎、粘连性疾病和意外子宫切除术。

病例报告

在本病例报告中,我们介绍了一名32岁患有大子宫肌瘤的女性,她因腹痛和月经过多而接受了剖腹子宫肌瘤切除术。子宫肌瘤切除术后4周,她因月经推迟被转诊至伊朗德黑兰阿亚图拉·塔莱加尼医院的产科门诊。她的β-人绒毛膜促性腺激素检测呈阳性。超声检查显示胎儿,估计孕周为6周4天。妊娠继续,无并发症。妊娠38周时,她接受了剖宫产,产下一名健康的新生儿。

结论

本病例报告支持了先前证明孕期子宫肌瘤切除术安全性的出版物。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47b8/11528293/075b6c4520cd/ijrb-22-673-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47b8/11528293/075b6c4520cd/ijrb-22-673-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47b8/11528293/075b6c4520cd/ijrb-22-673-g001.jpg

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1
Unexpected early pregnancy during myomectomy followed by successful term delivery: A case report.子宫肌瘤切除术中意外早期妊娠并足月成功分娩:一例报告
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The management of uterine leiomyomas.子宫平滑肌瘤的管理
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Global, regional, and national time trends in incidence, prevalence, years lived with disability for uterine fibroids, 1990-2019: an age-period-cohort analysis for the global burden of disease 2019 study.全球、地区和国家子宫纤维瘤发病率、患病率和残疾生存年数的时间趋势,1990-2019 年:对 2019 年全球疾病负担研究的年龄-时期-队列分析。
BMC Public Health. 2023 May 19;23(1):916. doi: 10.1186/s12889-023-15765-x.
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The effect of myomectomy on reproductive outcomes in patients with uterine fibroids: A retrospective cohort study.子宫肌瘤剔除术对子宫肌瘤患者生殖结局的影响:一项回顾性队列研究。
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Time to conceive after myomectomy: should we advise a minimum time interval? A systematic review.
子宫肌瘤剔除术后妊娠时间:我们是否应该建议一个最小时间间隔?系统综述。
Reprod Biomed Online. 2021 Sep;43(3):543-552. doi: 10.1016/j.rbmo.2021.05.016. Epub 2021 May 30.
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Uterine Fibroids and Pregnancy: How Do They Affect Each Other?子宫肌瘤与妊娠:它们如何相互影响?
Reprod Sci. 2022 Aug;29(8):2145-2151. doi: 10.1007/s43032-021-00656-6. Epub 2021 Jun 17.
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Growth pattern of uterine leiomyoma along pregnancy.子宫肌瘤在妊娠期间的生长模式。
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Rupture of a myomectomy site in the third trimester of pregnancy after myomectomy, septoplasty and cesarean section: A case report.子宫肌瘤剔除术、鼻中隔成形术及剖宫产术后妊娠晚期子宫肌瘤剔除部位破裂:一例报告
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Myoma and myomectomy: Poor evidence concern in pregnancy.子宫肌瘤与子宫肌瘤切除术:妊娠相关证据不足
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Uterine rupture in pregnancies following myomectomy: A multicenter case series.子宫肌瘤剔除术后妊娠子宫破裂:一项多中心病例系列研究。
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