柯萨奇病毒B3在不同环境条件下的存活情况。
Survival of coxsackievirus B3 under diverse environmental conditions.
作者信息
McGeady M L, Siak J S, Crowell R L
出版信息
Appl Environ Microbiol. 1979 May;37(5):972-7. doi: 10.1128/aem.37.5.972-977.1979.
The survival of coxsackievirus B3 was studied under various conditions of incubation. The comparative study demonstrated that coxsackievirus B3 was stable for 24h (less than 0.4-log decrease in titer) when suspended at neutral pH (6 or 23 degrees C) in the presence of 0.25% bovine serum albumin in saline regardless of whether the preparations were subjected to evaporation. Bovine serum albumin provided increased stability to the virus for each of the conditions tested. At 37 degrees C, evaporation greatly reduced the virus infectivity between 6 and 20 h of incubation. Nevertheless, coxsackievirus B3 was found to be stable for at least 24 h under conditions similar to those of a household environment, and its presence represents a potential biohazard to nonimmune persons. These data provide a rationale for using coxsackievirus B3 as a model for investigating the role of environmental surfaces in the transmission of enteroviral diseases.
研究了柯萨奇病毒B3在各种孵育条件下的存活情况。比较研究表明，当在中性pH值（6或23摄氏度）下，于含有0.25%牛血清白蛋白的盐溶液中悬浮时，无论制剂是否经受蒸发，柯萨奇病毒B3在24小时内是稳定的（滴度下降小于0.4个对数）。在每种测试条件下，牛血清白蛋白都提高了病毒的稳定性。在37摄氏度时，蒸发在孵育6至20小时之间极大地降低了病毒感染性。然而，发现柯萨奇病毒B3在类似于家庭环境的条件下至少24小时是稳定的，其存在对非免疫人群构成潜在的生物危害。这些数据为使用柯萨奇病毒B3作为模型来研究环境表面在肠道病毒疾病传播中的作用提供了理论依据。
Zotero 插件