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从一只非洲狮身上分离出的单核细胞增生李斯特氏菌的首次分子鉴定和全基因组测序。

First Molecular Identification and Whole Genome Sequencing of Listeria monocytogenes Isolated From an African Lion.

机构信息

Shanghai Animal Disease Control Center, Shanghai, China.

出版信息

Vet Med Sci. 2024 Nov;10(6):e70110. doi: 10.1002/vms3.70110.

Abstract

Listeria monocytogenes (LM) is a zoonotic pathogen that causes sporadic infectious listeriosis, which is a foodborne disease associated with consumption of contaminated food or feed. The internal organs of an African lion from a zoo in Shanghai were analysed to determine the cause of death. LM infection was suspected on the basis of the clinical symptoms and pathological changes and confirmed by polymerase chain reaction, whole genome sequencing and phylogenetic analysis. This is the first report of LM infection of an African lion in China.

摘要

李斯特菌(LM)是一种人畜共患病病原体,可引起散发性李斯特菌病,这是一种与食用受污染的食物或饲料有关的食源性疾病。为了确定死因,对来自上海动物园的一头非洲狮的内脏器官进行了分析。根据临床症状和病理变化怀疑感染了李斯特菌,并通过聚合酶链反应、全基因组测序和系统发育分析得到了证实。这是中国首例非洲狮李斯特菌感染的报告。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f645/11533306/f512402f8723/VMS3-10-e70110-g006.jpg

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