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基于磁性可回收催化剂:合成磺胺类药物的绿色策略

Based on magnetically recoverable catalysts: a green strategy to sulfonamides.

作者信息

Song Chuang, Kazemi Mosstafa

机构信息

Shandong Deyi New Materials Co., Ltd., Dezhou, 251500, Shandong , China.

Yanbian University, Yanji, 133000, Jilin, China.

出版信息

Mol Divers. 2024 Nov 4. doi: 10.1007/s11030-024-11030-4.

Abstract

The synthesis of sulfonamides, a class of compounds with significant pharmaceutical and medicinal applications, has seen remarkable advancements with the advent of magnetic nanocatalysts. Magnetic nanocomposites are one of the most efficient and widely used catalysts, and they are in complete harmony with the principles of modern green chemistry from the point of view of catalysis. These catalysts, typically composed of metal complexes supported on magnetic nanoparticles, offer unique advantages such as ease of recovery and reusability, which are crucial for sustainable and eco-friendly chemical processes. This review comprehensively examines recent developments in applying magnetic nanocatalysts to prepare sulfonamides. Key focus areas include the design and synthesis of various magnetic nanocatalysts (MNC), their catalytic performance in different reaction conditions, and mechanistic insights into their catalytic activity. By summarizing the latest research and technological advancements, this article aims to provide a valuable resource for researchers and practitioners in catalysis and pharmaceutical chemistry.

摘要

磺胺类化合物是一类具有重要制药和医学应用的化合物,随着磁性纳米催化剂的出现,其合成取得了显著进展。磁性纳米复合材料是最有效且应用最广泛的催化剂之一,从催化角度来看,它们与现代绿色化学原理完全契合。这些催化剂通常由负载在磁性纳米颗粒上的金属配合物组成,具有易于回收和可重复使用等独特优势,这对于可持续和环保的化学过程至关重要。本综述全面考察了应用磁性纳米催化剂制备磺胺类化合物的最新进展。重点关注领域包括各种磁性纳米催化剂(MNC)的设计与合成、它们在不同反应条件下的催化性能以及对其催化活性的机理见解。通过总结最新的研究和技术进展,本文旨在为催化和药物化学领域的研究人员及从业者提供有价值的参考资源。

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