用于监测贴壁哺乳动物细胞功能行为的基于静电纺丝氧化锡纳米纤维薄膜的传感装置。
Electrospun Stannic Oxide Nanofiber Thin-Film Based Sensing Device for Monitoring Functional Behaviors of Adherent Mammalian Cells.
作者信息
Kasiviswanathan Uvanesh, Kumar Chandan, Kumar Sahi Ajay, Kumar Amit, Jit Satyabrata, Sharma Neeraj, Kumar Mahto Sanjeev
出版信息
IEEE Trans Nanobioscience. 2025 Jan;24(1):120-126. doi: 10.1109/TNB.2024.3489353. Epub 2025 Jan 2.
PMID:39495679
Abstract
This study presents a biosensor utilizing electrospun SnO2 nanofiber films for real-time monitoring of C2C12 cells. The biosensor demonstrates sensitivity towards cellular behaviors, including adhesion, proliferation, and detachment. Alterations in semi-circle and dielectric properties are validated through Nyquist plot and an EEC model, highlighting the biosensor's potential for analyzing cellular dynamics.
摘要
本研究提出了一种利用电纺SnO2纳米纤维膜对C2C12细胞进行实时监测的生物传感器。该生物传感器对细胞行为，包括粘附、增殖和脱离表现出敏感性。通过奈奎斯特图和EEC模型验证了半圆和介电特性的变化，突出了该生物传感器在分析细胞动力学方面的潜力。
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