School of Animal, Plant and Environmental Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Pak J Pharm Sci. 2024 Sep;37(5):1177-1187.
Bulbine inflata is one of the species in the genus Bulbine that are yet to be documented for potential medicinal uses. Hence, we carried out its preliminary phytochemical profiling and investigated its antioxidant potential. The leaves were dried using air- and freeze-drying techniques and were extracted by water, methanol, ethyl acetate and hexane. Various common colour tests were used for the presence of phytochemicals. Some of the phytochemicals were further quantified. Phosphomolybdate, 2, 2 diphenyl-1-picryhydrazyl, hydrogen peroxide and metal chelating assays were used to assess the antioxidant potential of B. inflata. Tannin, flavonoids, phenols, glycosides, steroids, coumarins, quinones, saponins and terpenoids were detected phytochemicals in B. inflata leaves. The highest total phenolic, flavonoid and tannin contents, as well as total antioxidant capacity, were recorded for water extract. B. inflata showed moderate to high antioxidant activities against DPPH, HO and metal chelating. Freeze-dried samples presented with higher results than air-dried samples in most assays. The results showed the potential of B. inflata for medicinal uses and could expand the ethnomedicinal resources in the communities where it is prevalent and beyond.
膨胀 Bulbine 是 Bulbine 属中尚未被记录用于潜在药用用途的物种之一。因此，我们对其进行了初步的植物化学分析，并研究了其抗氧化潜力。叶片分别采用空气干燥和冷冻干燥技术进行干燥，并用水、甲醇、乙酸乙酯和正己烷进行提取。使用各种常见的显色试验来检测植物化学物质的存在。一些植物化学物质进一步进行了定量分析。使用磷钼酸盐、2,2-二苯基-1-苦肼基、过氧化氢和金属螯合测定法来评估 B. inflata 的抗氧化潜力。在 B. inflata 叶片中检测到单宁、类黄酮、酚类、糖苷、类固醇、香豆素、醌类、皂甙和萜类等植物化学物质。水提取物的总酚、类黄酮和单宁含量以及总抗氧化能力最高。B. inflata 对 DPPH、HO 和金属螯合具有中等至高的抗氧化活性。在大多数测定中，冷冻干燥样品的结果高于空气干燥样品。结果表明 B. inflata 具有药用潜力，可以扩展其在流行地区及其他地区的民族医学资源。
