Department of Cardiology, First People's Hospital of Linping District, Hangzhou, Zhejiang, P. R. China.
Science and Education Department, Guangxi Zhuang Autonomous Region Jiangbin Hospital, Nanning, Guangxi, P.R. China.
Medicine (Baltimore). 2024 Nov 1;103(44):e40413. doi: 10.1097/MD.0000000000040413.
Previous research on physical activity (PA) has mostly concentrated on a single or small number of activities, with scant coverage of the effects of PA on hypertension (HTN) and all-cause mortality. Most studies examining HTN in the elderly have been too small or shown contradictory findings. We conducted a cross-sectional study using 10 cycles of the National Health and Nutrition Examination Survey data from 1999 to 2018. Our sample consisted of respondents aged 65 years or older with HTN, who underwent thorough in-person home interviews. We used a questionnaire to assess their PA levels and divided them into 2 groups: physically active and inactive. We then used logistic analysis to determine the association between PA and death in HTN patients. The gender distribution was nearly equal among the 11,258 participants, with a mean age of 74.36 ± 5.88 years. Nearly 80% of the survey respondents identified as non-Hispanic White. Patients in the physically active group were less likely to suffer from co-morbidities than those in the inactive group. A negative correlation was found between physically active and systolic blood pressure (P < .0001) and a positive correlation between physically active and diastolic blood pressure (P = .0007). There was a much higher risk of death from any cause and heart disease in the inactive group in the uncorrected COX model (HR 2.96, CI 2.65-3.32, P < .0001; HR 3.48, CI 2.64-4.58, P < .0001). The risk of death from any cause and HTN mortality was still significantly higher in the physically inactive group, even after controlling for age, sex, and race or taking all covariates into account. These results have the potential to significantly impact healthcare practices, particularly in the field of geriatric care, by emphasizing the importance of PA in reducing the risk of HTN and mortality in aged patients. The present study underscores the significant benefits of PA in patients aged 65 years and older with HTN. Notably, it was found to reduce systolic blood pressure and have a positive impact on the decrease of all-cause and hypertensive mortality. These findings highlight the crucial role of PA in the health and longevity of aged patients with HTN.
先前关于身体活动（PA）的研究主要集中在单一或少数几种活动上，对 PA 对高血压（HTN）和全因死亡率的影响报道甚少。大多数研究高血压的老年患者规模太小或得出相互矛盾的结果。我们使用 1999 年至 2018 年的 10 轮国家健康和营养检查调查数据进行了横断面研究。我们的样本包括患有 HTN 且年龄在 65 岁或以上的受访者，他们接受了详细的上门家访。我们使用问卷评估他们的 PA 水平，并将他们分为两组：活跃组和不活跃组。然后，我们使用逻辑分析来确定 PA 与 HTN 患者死亡之间的关联。11258 名参与者的性别分布几乎相等，平均年龄为 74.36±5.88 岁。近 80%的调查受访者是非西班牙裔白人。与不活跃组相比，活跃组患者的合并症较少。PA 与收缩压呈负相关（P<0.0001），与舒张压呈正相关（P=0.0007）。在未经校正的 COX 模型中，不活跃组的全因死亡和心脏病死亡风险更高（HR 2.96，CI 2.65-3.32，P<0.0001；HR 3.48，CI 2.64-4.58，P<0.0001）。即使考虑到年龄、性别和种族或考虑所有协变量，不活跃组的全因死亡和 HTN 死亡率仍然显著更高。这些结果有可能对医疗保健实践产生重大影响，特别是在老年护理领域，强调 PA 在降低老年患者 HTN 和死亡率风险方面的重要性。本研究强调了 PA 对 65 岁及以上患有 HTN 的患者的显著益处。值得注意的是，它被发现可以降低收缩压，并对降低全因和高血压死亡率产生积极影响。这些发现突出了 PA 在患有 HTN 的老年患者健康和长寿方面的关键作用。
