Isik Ridvan, Kokar Serdar, Olgun Yucel, Sencan Savas, Gunduz Hakan
Division of Pain Medicine, Department of Physical Medicine and Rehabilitation, Sakarya Training and Research Hospital, Sakarya, TUR.
Division of Pain Medicine, Department of Physical Medicine and Rehabilitation, Marmara University, Istanbul, TUR.
Cureus. 2024 Oct 5;16(10):e70888. doi: 10.7759/cureus.70888. eCollection 2024 Oct.
The use of iodinated contrast media (ICM) inevitably increases in conjunction with the growing number of epidural steroid injection (ESI) administrations. The purpose of this study was to investigate the relationship between thyroid functions and ICM exposure through ESI procedures.
This is a prospective observational study.
The study was conducted at a university hospital pain management center.
This study was conducted between June 2022 and February 2023. Participants between the ages of 18 and 65 who had received an ESI at our outpatient pain clinic comprised the study's population. Thyroid function tests (free triiodothyronine (FT3), free thyroxine (FT4), and thyroid-stimulating hormone (TSH)) were measured before and three weeks after the procedure.
A total of 124 participants (80 women and 44 men) were analyzed. The average amount of contrast media administered was 1.34 ml. A significant increase was observed only in the FT4 value compared to pre-procedure (p = 0.017), and no patient developed thyroid disorders.
The current study presents an analysis of the relationship between ICM and thyroid functions in the ESI population.
随着硬膜外类固醇注射（ESI）给药次数的增加，碘化造影剂（ICM）的使用不可避免地增多。本研究的目的是通过ESI程序调查甲状腺功能与ICM暴露之间的关系。
这是一项前瞻性观察性研究。
该研究在一家大学医院疼痛管理中心进行。
本研究于2022年6月至2023年2月进行。在我们门诊疼痛诊所接受ESI的18至65岁参与者构成了研究人群。在手术前和手术后三周测量甲状腺功能测试（游离三碘甲状腺原氨酸（FT3）、游离甲状腺素（FT4）和促甲状腺激素（TSH））。
共分析了124名参与者（80名女性和44名男性）。造影剂的平均用量为1.34毫升。与术前相比，仅FT4值出现显著升高（p = 0.017），且没有患者出现甲状腺疾病。
本研究对ESI人群中ICM与甲状腺功能之间的关系进行了分析。
