中国若尔盖县蜱和牦牛的病原体鉴定。

Pathogenetic identification in ticks and yaks from Zoige County, China.

机构信息

College of Animal Science and Veterinary Medicine, Southwest Minzu University, Chengdu, China.

Animal Experiment Center, Institute of Animal Husbandry and Veterinary Science, Zhejiang Academy of Agricultural Sciences, Hangzhou, China.

出版信息

Front Cell Infect Microbiol. 2024 Oct 21;14:1474519. doi: 10.3389/fcimb.2024.1474519. eCollection 2024.

DOI:10.3389/fcimb.2024.1474519

PMID:39497923

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11532068/

Abstract

BACKGROUND

Ticks represent a significant vector for the transmission of infectious diseases, with the prevalence of tick-borne diseases becoming a prominent global health concern in recent decades. spp., spp., and Piroplasma have been identified as significant pathogens with the potential to impact human and animal health. However, there is a dearth of data concerning the prevalence of these pathogens in the eastern Tibetan Plateau, China.

METHODS

In this study, a total of 643 and 314 were identified through the application of morphological and molecular identification techniques on 957 ticks collected from yaks in Zoige County. The assessed of spp., spp., spp., and spp. was assessed in 957 ticks and 96 blood samples collected from yaks.

RESULTS

Significant discrepancies were observed in the positivity rates for the four pathogens among the tick species and sampling sites. The identification of different species within the four pathogens was based on the analysis of the 16S rRNA of spp., the and genes of spp., and the 18S rRNA of spp. and spp. The prevalence ranges of the four pathogens are 9.9-50.2%, 29.5-100%, 16.2-46.4%, and 14.5-58.4%, respectively.

CONCLUSION

In view of the growing zoonotic risks, further investigations into the prevalence of additional pathogens in ticks and animals, including livestock, in the eastern Tibetan Plateau, China, are essential.

摘要

背景

蜱虫是传染病传播的重要媒介，近年来蜱传疾病的流行已成为全球关注的一个突出的健康问题。硬蜱属、璃眼蜱属和巴贝斯虫属已被确定为重要的病原体，可能对人类和动物健康造成影响。然而，关于中国东部青藏高原这些病原体的流行情况，数据仍然匮乏。

方法

本研究通过对从若尔盖县牦牛身上采集的 957 只蜱虫进行形态学和分子鉴定技术，共鉴定出 643 只硬蜱属和 314 只璃眼蜱属。对 957 只蜱虫和 96 份牦牛血液样本进行了评估，以确定硬蜱属、璃眼蜱属、无形体属和泰勒虫属的感染情况。

结果

在不同的蜱种和采样地点，这四种病原体的阳性率存在显著差异。通过对硬蜱属的 16S rRNA、璃眼蜱属的和基因以及无形体属和泰勒虫属的 18S rRNA 进行分析，确定了这四种病原体的不同种系。这四种病原体的流行范围分别为 9.9-50.2%、29.5-100%、16.2-46.4%和 14.5-58.4%。