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评估新冠疫情期间世卫组织东南亚区域公共卫生实验室的准备情况及应对措施:经验教训与未来方向

Assessment of public health laboratory preparedness and response in WHO South-East Asia region during the COVID-19 pandemic: lessons learned and future directions.

作者信息

Inbanathan Francis Y, Wijesinghe Pushpa R, Naidoo Dhamari, Buddha Nilesh, Salvador Edwin Ceniza, Le Khanh Kim, Dhawan Sandhya, Blacksell Stuart D

机构信息

World Health Organization South-East Asian Region Office, Delhi, India.

Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.

出版信息

Lancet Reg Health Southeast Asia. 2024 Oct 19;31:100496. doi: 10.1016/j.lansea.2024.100496. eCollection 2024 Dec.

Abstract

This Health Policy reviews the preparedness and response of public health laboratories in the WHO South-East Asia Region (SEAR) during the COVID-19 pandemic. Through a scoping review and in-depth interviews with key stakeholders, the study identifies successes, challenges, and lessons learned from available literature and the perspective of senior laboratory leaders. Key themes include human resources, health information systems, diagnostic capacity, public risk communication, biosafety, biosecurity, funding, and laboratory network coordination. The findings provide a comprehensive overview of the adaptive capacities of laboratories, the contextual factors influencing their response, and the implications for future pandemic preparedness. This study demonstrates the resilience and adaptability of diagnostic networks in the face of a pandemic but also emphasises the need for strategic resource allocation, highlighting the importance of flexible and scalable networks in managing public health crises. The success of these deployments highlights the necessity for continual investment and coordination of national, regional, and global resources in diagnostic infrastructure to improve preparedness for future public health crises.

摘要

本卫生政策回顾了世卫组织东南亚区域(SEAR)公共卫生实验室在新冠疫情期间的防范和应对情况。通过范围界定审查以及与关键利益攸关方的深入访谈,该研究从现有文献以及高级实验室领导人的视角确定了成功经验、挑战和汲取的教训。关键主题包括人力资源、卫生信息系统、诊断能力、公共风险沟通、生物安全、生物安保、资金以及实验室网络协调。研究结果全面概述了实验室的适应能力、影响其应对的背景因素以及对未来大流行防范工作的启示。本研究展示了诊断网络在面对大流行时的韧性和适应性,但也强调了战略资源分配的必要性,凸显了灵活且可扩展的网络在管理公共卫生危机方面的重要性。这些部署的成功凸显了持续投资以及协调国家、区域和全球资源用于诊断基础设施建设以提高对未来公共卫生危机防范能力的必要性。

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