导管内乳头状黏液性肿瘤：治疗概述。
Intraductal papillary mucinous neoplasm: Overview of management.
机构信息
MBBS, FRACS, General and Hepatopancreatobiliary Surgeon, Department of Surgery, Alfred Hospital, Melbourne, Vic; Hepatopancreatobiliary Surgeon, Department of Surgery, Royal Melbourne Hospital, Melbourne, Vic; General Surgeon, Department of Surgery, Grampians Health, Ballarat, Vic.
MBChB, PhD, FRACS, General and Hepatopancreatobiliary Surgeon, Department of Surgery, Royal Melbourne Hospital, Melbourne, Vic; Hepatopancreatobiliary Surgeon, Peter MacCallum Cancer Centre, Melbourne, Vic; Honorary Academic Appointment, Department of Surgery, University of Auckland, Auckland, New Zealand.
出版信息
Aust J Gen Pract. 2024 Nov;53(11):835-839. doi: 10.31128/AJGP-05-23-6822.
BACKGROUND
Intraductal papillary mucinous neoplasm (IPMN) of the pancreas is increasingly being diagnosed incidentally on imaging. It has malignant potential, making it vital to establish the correct diagnosis, assess its malignant risk and follow a management strategy to prevent development of invasive carcinoma of the pancreas.
OBJECTIVE
This review focuses on the epidemiology, natural history, risk factors, diagnosis and management of IPMN of the pancreas, and will provide practical points for general practitioners.
DISCUSSION
IPMN of the pancreas can transform into invasive pancreatic carcinoma at a low rate of approximately 2%/year. Upon diagnosis of IPMN, it is risk stratified based on the presence of worrisome or high-risk stigmata, which guides further management. Management needs to be individualised based on IPMN and patient factors due to limitations with the current diagnostic tools.
背景
胰腺内导管乳头状黏液性肿瘤（IPMN）在影像学检查中越来越多地被偶然发现。它具有恶性潜能，因此确定正确的诊断、评估其恶性风险并遵循管理策略以预防胰腺浸润性癌的发生至关重要。
目的
本综述重点介绍胰腺 IPMN 的流行病学、自然史、危险因素、诊断和管理，并为全科医生提供实用要点。
讨论
胰腺 IPMN 以每年约 2%的低速率转化为浸润性胰腺癌。在诊断 IPMN 时，根据存在令人担忧或高危特征来进行风险分层，这指导进一步的管理。由于目前诊断工具的局限性，需要根据 IPMN 和患者因素进行个体化管理。
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